- 4-Hydroxyphenylboronic acid
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- $34.00 / 1kg
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2024-04-08
- CAS:71597-85-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 4-Hydroxyphenylboronic acid Basic information |
| | 4-Hydroxyphenylboronic acid Chemical Properties |
| Melting point | >230 °C (lit.) | | Boiling point | 351.4±44.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | soluble in Acetonitrile, DMSO, Methanol | | form | Powder | | pka | 9.09±0.10(Predicted) | | color | Off-white to light brown | | Water Solubility | 25 g/L | | BRN | 2963491 | | InChIKey | COIQUVGFTILYGA-UHFFFAOYSA-N | | CAS DataBase Reference | 71597-85-8(CAS DataBase Reference) |
| | 4-Hydroxyphenylboronic acid Usage And Synthesis |
| Chemical Properties | off-white to light brown powder | | Uses | 4-Hydroxyphenylboronic acid can be used as a reactant in:
- Suzuki-Miyaura coupling and Stille coupling reactions.
- Palladium-catalyzed aminocarbonylation and cross-coupling reactions.
- Suzuki reaction for preparation of bio-supported palladium nanoparticles as phosphine-free catalysts.
- Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles.
It can also be used to prepare/promote:
- PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis inhibitor).
- Rod-like dendronized polymers containing G4 and G5 ester dendrons via macromonomer approach by living ROMP.
- Estrone-derived cyclopamine analogs as Sonic Hedgehog signaling inhibitors for anti-cancer chemotherapeutics.
- Enzymatic inhibitors for the treatment of Gram-negative bacterial infections.
- Oligoarenes by Suzuki-Miyaura palladium-catalyzed cross-coupling.
| | Uses | 4-Hydroxybenzeneboronic acid is used for Suzuki-Miyaura coupling and Stille coupling and potential for introducing different alkyl groups, palladium-catalyzed aminocarbonylation and cross-coupling reactions, bio-supported palladium nanoparticles as phosphine-free catalyst for Suzuki reaction in water and Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles. It is also used in preparation of rod-like dendronized polymers. | | Synthesis Reference(s) | Tetrahedron Letters, 37, p. 6705, 1996 DOI: 10.1016/S0040-4039(96)01468-2 |
| | 4-Hydroxyphenylboronic acid Preparation Products And Raw materials |
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