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Linoleic acid

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Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Linoleic acid
CAS:60-33-3
Purity:GC>=98% Package:0.2ml
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Linoleic Acid
CAS:60-33-3
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Linoleic acid
CAS:60-33-3
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
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Products Intro: Product Name:Linoleic acid
CAS:60-33-3
Purity:99.9% Package:1KG;5USD
Company Name: career henan chemical co
Tel: +86-371-86658258
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Products Intro: Product Name:Linoleic acid
CAS:60-33-3
Purity:98% Package:1kg;8USD

Lastest Price from Linoleic acid manufacturers

  • Linoleic acid
  • US $8.00 / kg
  • 2018-12-17
  • CAS:60-33-3
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 10MT
  • Linoleic acid
  • US $8.00 / kg
  • 2018-12-17
  • CAS:60-33-3
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 10MT
Linoleic acid Basic information
Linoleic acid and its function Brief Introduction Pharmaceutical effects Linoleic acid sources and food Production
Product Name:Linoleic acid
Synonyms:9,12-octadecadienoic;LINOLEIC ACID FREE ACID CELL CULTURE*TES TED;ETHYL VINYL KETONE 95+%;LINOLEIC ACID, STANDARD FOR GC;LINOLEIC ACID FREE ACID APPROX. 60%;LINOLEIC ACID FREE ACID, >=99%;LINOLEIC ACID, NATURAL;Linoleic acid, pract.
CAS:60-33-3
MF:C18H32O2
MW:280.45
EINECS:200-470-9
Product Categories:Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives;Antioxidant;Biochemistry;Higher Fatty Acids & Higher Alcohols;Unsaturated Higher Fatty Acids;Natural Plant Extract;Biological and chemical;Cell Culture;Lipids and Lipid Carriers;Reagents and Supplements
Mol File:60-33-3.mol
Linoleic acid Structure
Linoleic acid Chemical Properties
Melting point -5 °C
Boiling point 229-230 °C16 mm Hg(lit.)
density 0.902 g/mL at 25 °C(lit.)
refractive index n20/D 1.466(lit.)
FEMA 3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
Fp >230 °F
storage temp. 2-8°C
solubility NaOH: soluble1M
pka4.77(at 25℃)
form liquid
color Clear yellow
Water Solubility INSOLUBLE
FreezingPoint -5℃
Sensitive Air Sensitive
λmax270nm(H2O)(lit.)
Merck 14,5505
BRN 1727101
Stability:Stability Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference60-33-3(CAS DataBase Reference)
NIST Chemistry Reference9,12-Octadecadienoic acid (Z,Z)-(60-33-3)
EPA Substance Registry System9,12-Octadecadienoic acid (9Z,12Z)-(60-33-3)
Safety Information
Hazard Codes Xi
Risk Statements 36-36/37/38
Safety Statements 26-24/25-36-37/39
RIDADR UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 1
RTECS RF9990000
8-10-23
TSCA Yes
HS Code 29161500
Hazardous Substances Data60-33-3(Hazardous Substances Data)
MSDS Information
ProviderLanguage
cis-9,cis-12-Octadecadienoic acid English
SigmaAldrich English
ACROS English
ALFA English
Linoleic acid Usage And Synthesis
Linoleic acid and its functionLinoleic acid is unsaturated omega-6 fatty acid usually found in corn, safflower, and sunflower oils. As it cannot be synthesized in vivo and has a defined metabolic significance, Linoleic acid is accepted as an essentical nutrient. Linolenic acid gives rise to arachidonic acid, which is the major precursor of a series of bioactive metabolites called eicosanoids, which regulate physiological processes in large scale such as prostaglandins, thromboxane A2, prostacyclin I2, leukotriene B4 and anandamide providing the body anti-inflammatory, moisturizing and healing support.
In 1930, Scientist reported that the rats exhibited scaly skin lesions, impaired growth, tail necrosis, and renal degeneration by the lack of linoleic acid, and the return of this fatty acid to the animal’s diet cured the lesions. Administration of only 1 to 2% of dietary calories in the form of linoleic acid will support normal growth and development and prevent the clinical appearance of essential fatty acid deficiency (EFAD). Linoleic acid deficiency possibly happens in infants fed skimmed milk, in patients with chronic fat malabsorption, and in those undergoing total parenteral nutrition, which will cause poor growth and development in infants and dermatitis in adults.
Brief IntroductionLinoleic acid is named cis-9, 12-octadecadienoic acid, can also use △ to denote double bond, thus being named △ 9, 12-octadecadienoic acid. Alternatively, it can be simply expressed as 9C, 12C-18: 2 or C18: 2.
Linoleic acid in foods is important for human body to maintain many physiological functions such as the synthesis of phospholipids and other lipid metabolism, etc., being capable f significantly lower the effect of serum cholesterol. It can correct the growth arrest, skin and hair abnormalities, abnormal serum and adipose tissue composition of experimental animals due to lack of essential fatty acids. Lack of it in human beings can affect cell membrane function. Lack in infants can cause eczema. It is currently the major unsaturated fatty acids used to prevent and treat hyperlipidemia. Plant fat is the main source of linoleic acid, of which soybean oil, corn oil and cottonseed oil content is particularly rich. The content in vegetable oil (except palm oil), fish fat and poultry fat is also high. It is generally recommended that the amount of dietary linoleic acid should be equivalent to more than 2% to 3% of the total dietary calories.
Pharmaceutical effectsLinolenic acid is the unsaturated acids obtained from the extraction and vacuum distillation of the saponification product of soybean oil. It contains over 65% of pure linoleic acid as well as vitamin E being as an antioxidant. Linoleic acid can react with cholesterol to become esters, which is more easily transported, metabolized and excreted, thus reducing blood cholesterol levels. It can also reduce the triglycerides content in the blood. Unsaturated fatty acids may change the distribution of cholesterol in the body, making it deposited in the tissue outside the vessel wall, further reducing the cholesterol content of the vessel wall for preventing and treating atherosclerosis.
Linoleic acid sources and food
Fatty acid Double Bonds Sources
Linoleic acid n-6 Vegetable oils, margarines, grain
α- linolenic acid
n-3
 
  Green leaves, linseed, soybean and canola oil
EPA, DHA   Marine animals, cod liver oil and fish oil
  Safflower, sunflower, soybean and corn oils are the major sources of omega-6 fatty acids (linoleic acid), which makes up 85 to 90 percent of caloric sources. Pine nuts, pecans and Brazil nuts are also high in linoleic acid. The ideal ratio of omega-3(linolenic acid) and omega-6(linoleic acid) fatty acids is 2:1 to 4:1; however, the standard Western diet provides omega-6(linoleic acid) polyunsaturated fatty acids in excess of 14 times that of omega-3 fatty acids (linolenic acid).
ProductionLinoleic acid is present in the form of glycerides inside the animal body together with other fatty acids. The content in animal fat is generally low; for example, 1.8% iin butter, 6% in lard; some kinds of vegetable oils have high content such as 26% in peanut oil, and 15.8 in rape oil while the soybean fatty acids are mainly linoleic acid. The general composition of soybean fatty acids are as follows: oleic acid 15-33% linoleic acid 53-56% linolenic acid 5-9% palmitic acid 7-11% stearic acid and 2-6% Carbon 20- or more acids. The 0.3-3% soybean oil, will give approximately 5-10% of the oil foot and soap foot during the refining process. Half of the soya bean oil soap is useful fatty acids, while the fatty acids in the soaps are essentially the same as the fatty acid composition of the soya bean oil. Therefore, the use of soybean oil soap for extraction of linoleic acid is an important way to comprehensive utilize the soybean oil.
Chemical PropertiesLiquid at room temperature, colorless
Useslinoleic acid (vitamin F) is also known as omega-6. An emulsifier, it is also cleansing, emollient, and skin conditioning. Some formulations incorporate it as a surfactant. Linoleic acid prevents dryness and roughness. A deficiency of linoleic acid in the skin is associated with symptoms similar to those characterizing eczema, psoriasis, and a generally poor skin condition. In numerous laboratory studies where a linoleic acid deficiency was induced, a topical application of linoleic acid in its free or esterified form quickly reversed this condition. In addition, there is some evidence in laboratory tests that linoleic acid may inhibit melanin production by decreasing tyrosinase activity and suppressing melanin polymer formation within melanosomes. Linoleic acid is an essential fatty acid found in a variety of plant oils, including soybean and sunflower.
DefinitionChEBI: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.
General DescriptionColorless to straw colored liquid. A polyunsaturated fatty acid essential to human diet.
Air & Water ReactionsSensitive to air and light. . Oxidizes across carbon double bonds
Reactivity ProfileLinoleic acid reacts to neutralize bases. May react vigorously with oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.
Fire HazardFlash point data for Linoleic acid are not available. Linoleic acid is probably combustible.
Tag:Linoleic acid(60-33-3) Related Product Information
Linolenic acid FATTY ACID KIT Oleic acid Hyaluronic acid METHYL LINOLEATE Methyl Oleate Docosahexaenoic Acid OCTADECENEDIOIC ACID Arachidonic acid VIGABATRIN LINOLEIC ACID PROPYL ESTER TRIBUTYLTIN LINOLEATE LINOLEIC ANHYDRIDE CETYL LINOLEATE N-BUTYL LINOLEATE Cholesteryl linoleate TRILINOLEIN ISOPROPYL LINOLEATE