| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
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| | ANTI-HUMAN NKB1 Basic information |
| Product Name: | ANTI-HUMAN NKB1 | | Synonyms: | Anti-GEM, (N-terminal) antibody produced in rabbit;Anti-GEM antibody produced in rabbit;Monoclonal Anti-GEM antibody produced in mouse;ANTI-HU KIR (NKB1);ANTI-HUMAN KILLER INHIBITORY RECEPTOR, NKB1;ANTI-HUMAN NKB1;ANTI-KIR;ANTI-NKB1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN NKB1 Structure]() |
| | ANTI-HUMAN NKB1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | WGK 1 | | Storage Class | 10 - Combustible liquids |
| | ANTI-HUMAN NKB1 Usage And Synthesis |
| Biological Activity | GEM (GTP binding protein overexpressed in skeletal muscle) is a guanosine triphosphate (GTP)-binding protein. It controls voltage gated Ca2+ channels and cytoskeleton dynamics. Overexpression of GEM causes disruption of stress fiber, changes in cell shape and neurite elongation in interphase cells. In addition, it is also involved in actin remodelling during mitosis. In Timothy syndrome, overexpression of GEM leads to inactivation of RhoA, thereby preventing dendritic retraction. GEM might also be associated with cell invasiveness. In HTLV-1 retrovirus (human T-cell leukemia virus type 1) infection, GEM is involved in cell-to-cell viral transmission. |
| | ANTI-HUMAN NKB1 Preparation Products And Raw materials |
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