- PATULIN
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- $56.00 / 1mg
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2025-11-04
- CAS:149-29-1
- Min. Order:
- Purity: 99.91%
- Supply Ability: 10g
- PATULIN
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- $0.00 / 25KG
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2025-04-04
- CAS:149-29-1
- Min. Order: 25KG
- Purity: 97%
- Supply Ability: 1tone
- PATULIN
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- $15.00 / 1KG
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2021-07-02
- CAS:149-29-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | PATULIN Basic information |
| | PATULIN Chemical Properties |
| Melting point | 108-111 °C | | alpha | D21 -6.2° (chloroform) | | Boiling point | 197.46°C (rough estimate) | | density | 1.1993 (rough estimate) | | refractive index | 1.4300 (estimate) | | Fp | 2℃ | | storage temp. | −20°C | | solubility | ethyl acetate: soluble50mg/mL | | pka | 11.69±0.20(Predicted) | | form | Crystals or Crystalline Powder | | color | White | | Merck | 13,7125 | | BRN | 149675 | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. | | CAS DataBase Reference | 149-29-1(CAS DataBase Reference) | | IARC | 3 (Vol. 40, Sup 7) 1987 | | EPA Substance Registry System | Patulin (149-29-1) |
| | PATULIN Usage And Synthesis |
| Description | Spergillus and Penicillium species.
Patulin is also an animal carcinogen, inhibits K1-uptake into
erythrocytes, and inhibits various forms of Na1/K1-ATPase. | | Chemical Properties | white crystals or fine crystalline powder | | Uses | Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. | | Uses | An inhibitor of protein prenylation | | Definition | ChEBI: A furopyran and lactone that is 2H-pyran-3(6H)-ylidene)acetic acid which is syubstituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give
he corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic. | | Purification Methods | Crystallise patulin from *C6H6, Et2O, EtOH or chloroform. It sublimes at 90o/high vacuum [Bergel et al. J Chem Soc 415 1944]. [Beilstein 18 III/IV 1184, 18/3 V 5.] (Highly TOXIC). | | References | [1] HUAN JIN. p53 activation contributes to patulin-induced nephrotoxicity via modulation of reactive oxygen species generation.[J]. Scientific Reports, 2016: 24455. DOI:10.1038/srep24455
[2] NIDHAL ZOUAOUI . Cytotoxic effects induced by patulin, sterigmatocystin and beauvericin on CHO–K1 cells[J]. Food and Chemical Toxicology, 2016, 89: Pages 92-103. DOI:10.1016/j.fct.2016.01.010
[3] MANEL BOUSSABBEH . Tissue oxidative stress induced by patulin and protective effect of crocin[J]. Neurotoxicology, 2016, 53: Pages 343-349. DOI:10.1016/j.neuro.2015.11.005
[4] Y. PILLAY . Patulin triggers NRF2-mediated survival mechanisms in kidney cells[J]. Toxicon, 2015, 99: Pages 1-5. DOI:10.1016/j.toxicon.2015.03.004
[5] MANEL BOUSSABBEH. Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway.[J]. Toxicological Sciences, 2015, 144 2: 328-337. DOI:10.1093/toxsci/kfu319 |
| | PATULIN Preparation Products And Raw materials |
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