CalFluor 488 Azide

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Products Intro: Product Name:CalFluor 488 azide
CAS:1798305-98-2
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Products Intro: Product Name:CalFluor 488 Azide
CAS:1798305-98-2
Purity:90% Package:$586.9/1mg;$2386.9/5mg;Bulk package Remarks:90%
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Products Intro: Product Name:CalFluor 488 Azide
CAS:1798305-98-2
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Products Intro: Product Name:CalFluor 488 Azide;CalFluor 488 N3
CAS:1798305-98-2
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Products Intro: Product Name:CalFluor 488 Azide
CAS:1798305-98-2
Purity:98% Package:5g;10g;20g;100g;100kg
CalFluor 488 Azide Basic information
Product Name:CalFluor 488 Azide
Synonyms:CalFluor 488 Azide;CalFluor 488 N3;CalFluor 488 Azide (CCT-1369)
CAS:1798305-98-2
MF:C37H49N5O13S2
MW:835.94
EINECS:
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Mol File:1798305-98-2.mol
CalFluor 488 Azide Structure
CalFluor 488 Azide Chemical Properties
solubility Water, DMSO
form Solid
color Orange to red
AppearanceYellow to orange amorphous solid
Safety Information
MSDS Information
CalFluor 488 Azide Usage And Synthesis
DescriptionCalFluor 488 Azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. This azide probe is not fluorescent until it is reacted with alkynes. CalFluor 488 Azide is a water-soluble probe, and its excitation band is a good match for the 488 nm laser lines (with FITC filter sets).
UsesCalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References[1] Neugebauer ME, et al. Reaction pathway engineering converts a radical hydroxylase into a halogenase. Nat Chem Biol. 2022 Feb;18(2):171-179. DOI:10.1038/s41589-021-00944-x
[2] Hu J, et al. Chiral lipid bilayers are enantioselectively permeable. Nat Chem. 2021 Aug;13(8):786-791. DOI:10.1038/s41557-021-00708-z
Spectrally Similar DyesFAM, Alexa Fluor® 488, Atto™ 488, CF™ 488A dyes, DyLight™488
CalFluor 488 Azide Preparation Products And Raw materials
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