Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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3bsc@sina.com |
Products Intro: |
Product Name:SCH 39166 hydrobroMide;(6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-Methyl-5H-benzo[d]naphth[2,1-b]azepin-12-olhydrobroMide Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 18521732826; |
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market@aladdin-e.com |
Products Intro: |
Product Name:SCH 39166 hydrobromide CAS:1227675-51-5 Purity:98% Package:10mg/RMB 3862.90;50mg/RMB 9420.00;1mg/RMB 617.90
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
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info@emmx.com |
Products Intro: |
Product Name:SCH 39166 hydrobromide Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Basic information |
Product Name: | (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE | Synonyms: | SCH 39166 HYDROBROMIDE;(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE | CAS: | 1227675-51-5 | MF: | C19H21BrClNO | MW: | 394.74 | EINECS: | | Product Categories: | Dopamine receptor | Mol File: | Mol File | |
| (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Chemical Properties |
storage temp. | Desiccate at RT | solubility | DMSO: Slightly Soluble; Methanol: Slightly Soluble; Water: Slightly Soluble | form | A solid | Stability: | Hygroscopic |
| (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Usage And Synthesis |
Description | SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol intake in Sardinian alcohol-preferring rats and sucrose intake in water-deprived and water-sated rats without affecting food or total fluid intake. SCH 39166 also suppresses cocaine-induced arrhythmias in anesthetized dogs. | Uses | SCH 39166 is a dopamine D1/D5 receptor antagonist used in the treatment of schizophrenia, cocaine addiction and obesity. | storage | Desiccate at RT |
| (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Preparation Products And Raw materials |
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