| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:BIHC >=98% (HPLC)
CAS:1642826-40-1
Purity:NULL Package:25mg;5mg Remarks:NULL
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| | BIHC >=98% (HPLC) Basic information |
| | BIHC >=98% (HPLC) Chemical Properties |
| Boiling point | 808.7±65.0 °C(Predicted) | | density | 1.535±0.06 g/cm3(Predicted) | | pka | 4.20±1.00(Predicted) |
| | BIHC >=98% (HPLC) Usage And Synthesis |
| Uses | BIHC is a Her2-CD3 bispecific antibody constructed from a single-domain antibody targeting Her2 and a single-chain variable fragment (Fv) targeting CD3, formatted in an IgG-like structure. BIHC demonstrates effective antitumor activity in vivo, specifically binding to tumor cells expressing Her2 and efficiently eliminating Her2-positive cancer cells by recruiting T cells, thus being used in the study of Her2-positive cancers[1]. | | References | [1] Xing J, et al. BiHC, a T-Cell-Engaging Bispecific Recombinant Antibody, Has Potent Cytotoxic Activity Against Her2 Tumor Cells. Transl Oncol. 2017 Oct;10(5):780-785. DOI:10.1016/j.tranon.2017.07.003 |
| | BIHC >=98% (HPLC) Preparation Products And Raw materials |
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