| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Rinvanil >=98% (HPLC)
CAS:457643-60-6
Purity:NULL Package:1ea;25mg;5mg Remarks:NULL
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Rinvanil
CAS:457643-60-6
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| | Rinvanil >=98% (HPLC) Basic information |
| Product Name: | Rinvanil >=98% (HPLC) | | Synonyms: | Rinvanil >=98% (HPLC);9-Octadecenamide, 12-hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-, (9Z,12R)-;Rinvanil | | CAS: | 457643-60-6 | | MF: | C26H43NO4 | | MW: | 433.62 | | EINECS: | | | Product Categories: | | | Mol File: | 457643-60-6.mol |  |
| | Rinvanil >=98% (HPLC) Chemical Properties |
| Boiling point | 633.0±55.0 °C(Predicted) | | density | 1.025±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 9.76±0.20(Predicted) | | form | oil | | color | colorless to yellow |
| | Rinvanil >=98% (HPLC) Usage And Synthesis |
| Biological Activity | Rinvanil is a Capsaicin analogue th at potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes.', 'TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1. |
| | Rinvanil >=98% (HPLC) Preparation Products And Raw materials |
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