GMB-475 manufacturers
- GMB-475
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- $0.00 / 100mg
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2024-06-07
- CAS:2490599-18-1
- Min. Order: 1mg
- Purity: 98%
- Supply Ability: 100G
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| | GMB-475 Basic information |
| Product Name: | GMB-475 | | Synonyms: | (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;GMB-475;Bcr-Abl,GMB-475,PROTACs,GMB 475,Apoptosis,Inhibitor,inhibit,GMB475 | | CAS: | 2490599-18-1 | | MF: | C43H46F3N7O7S | | MW: | 861.94 | | EINECS: | | | Product Categories: | | | Mol File: | 2490599-18-1.mol |  |
| | GMB-475 Chemical Properties |
| Boiling point | 1029.7±65.0 °C(Predicted) | | density | 1.337±0.06 g/cm3(Predicted) | | solubility | DMSO:145.4(Max Conc. mg/mL);168.69(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);58.01(Max Conc. mM) | | pka | 13.50±0.46(Predicted) |
| | GMB-475 Usage And Synthesis |
| Description | GMB-475 acts as a degrader of BCR-ABL 1 tyrosine kinase and as a recruiter of the E3 ligase Von Hippel Lindau (VHL) resulting in ubiquitination and subsequent degradation of oncogenic fusion proteins. | | storage | Store at -20°C |
| | GMB-475 Preparation Products And Raw materials |
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