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| | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Basic information |
| Product Name: | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline | | Synonyms: | Solifenacin Related Compound 11;(S)-1,2,3,4- four-1- phenylhydrogenisoquinoline;Solifenacin Succinate interMediate F;(S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline, Solifenacin intermediate;Solifenacin Impurity A;(S)-1,2,3,4-Tetrahydro-1-phenylisoquinoline,99%e.e.;(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;(S)-1,2,3,4-TETRAHYDRO-1-PHENYLISOQUINOLINE | | CAS: | 118864-75-8 | | MF: | C15H15N | | MW: | 209.29 | | EINECS: | 1806241-263-5 | | Product Categories: | Other APIs;Aromatics;Chiral Reagents;Heterocycles;Isotope Labeled Compounds;API intermediates;Aromatics Compounds | | Mol File: | 118864-75-8.mol |  |
| | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties |
| Melting point | 80-82°C | | Boiling point | 338°C | | density | 1.065 | | Fp | 167°C | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) | | form | Solid | | pka | 8.91±0.40(Predicted) | | color | White to Off-White | | CAS DataBase Reference | 118864-75-8(CAS DataBase Reference) |
| | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. | | Uses | Solifenacin (S676700) intermediate. | | Uses | Labelled Solifenacin intermediate |
| | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Preparation Products And Raw materials |
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