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2,5-Dihydroxybenzoic acid

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Tel: 021-60451682
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Products Intro: Product Name:2,5-Dihydroxybenzoic acid
CAS:490-79-9
Purity:97% Package:10G 100G 1KG 25KG
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Products Intro: Product Name:2,5-Dihydroxybenzoic acid
CAS:490-79-9
Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS:490-79-9
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
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Products Intro: Product Name:490-79-9
CAS:490-79-9
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CAS:490-79-9
Purity:As coa Package:As request Remarks:490-79-9

2,5-Dihydroxybenzoic acid manufacturers

2,5-Dihydroxybenzoic acid Basic information
Product Name:2,5-Dihydroxybenzoic acid
Synonyms:Hydroguinonecarboxylicacid;Kyselina 2,5-dihydroxybenzoova;Kyselina gentisinova;kyselina2,5-dihydroxybenzoova;kyselinagentisinova;Salicylic acid, 5-hydroxy-;2,5-Dihydroxybenzoic acid, 99% 5GR;MesalaMine IMpurity G
CAS:490-79-9
MF:C7H6O4
MW:154.12
EINECS:207-718-5
Product Categories:Analytical Chemistry;Mass Spectrometry;Organic acids;Matrix Materials (MALDI-TOF-MS);UltraPure MALDI Matrices;Inhibitors;Armoracia rusticana (Horseradish);Building Blocks;C7;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Citrus aurantium (Seville orange);Humulus lupulus (Hops);Hypericum perforatum (St John′;Nutrition Research;Organic Building Blocks;Panax ginseng;Phytochemicals by Plant (Food/Spice/Herb);s wort);Vaccinium myrtillus (Bilberry)
Mol File:490-79-9.mol
2,5-Dihydroxybenzoic acid Structure
2,5-Dihydroxybenzoic acid Chemical Properties
Melting point 204-208 °C(lit.)
Boiling point 237.46°C (rough estimate)
density 1.3725 (rough estimate)
refractive index 1.6400 (estimate)
storage temp. Store below +30°C.
solubility It is soluble in alcohol and ether.
pka2.97(at 25℃)
form Crystalline Powder
color White to light beige
Water Solubility soluble
Merck 14,4398
BRN 2209119
InChIKeyWXTMDXOMEHJXQO-UHFFFAOYSA-N
CAS DataBase Reference490-79-9(CAS DataBase Reference)
NIST Chemistry Reference2,5-Dihydroxybenzoic acid(490-79-9)
EPA Substance Registry SystemBenzoic acid, 2,5-dihydroxy- (490-79-9)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS LY3850000
Hazard Note Harmful
TSCA Yes
HS Code 29182990
MSDS Information
ProviderLanguage
2,5-Dihydroxybenzoic acid English
SigmaAldrich English
ACROS English
ALFA English
2,5-Dihydroxybenzoic acid Usage And Synthesis
DescriptionGentisic acid is a dihydroxy benzoic acid. It is a derivative of benzoic acid and a minor (1 %) product of the metabolic break down of aspirin, excreted by the kidneys.
It is also found in the African tree Alchornea cordifolia and in wine.
Chemical Propertieswhite to light beige crystalline powder
UsesMedicine, as sodium gentisate (analgesic).
DefinitionChEBI: A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.
Production MethodsGentisic acid is produced by carboxylation of hydroquinone.
C6H4(OH)2 + CO2 → C6H3(CO2H)(OH)2
This conversion is an example of a Kolbe–Schmitt reaction.
ApplicationAs a hydroquinone , gentisic acid is readily oxidized and is used as an antioxidant excipient in some pharmaceutical preparations. In the laboratory, it is used as a sample matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry , and has been shown to conveniently detect peptides incorporating the boronic acid moiety by MALDI .
Synthesis Reference(s)Journal of the American Chemical Society, 72, p. 3292, 1950 DOI: 10.1021/ja01163a521
Safety ProfilePoison bp intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification MethodsCrystallise gentisic acid from hot water or *benzene/acetone. Dry it in a vacuum desiccator over silica gel. [Beilstein 10 H 384, 10 IV 1441.]
2,5-Dihydroxybenzoic acid Preparation Products And Raw materials
Raw materialsHydroquinone
Preparation ProductsFlecainide-->Methyl 2,5-dihydroxybenzoate-->3,6-DIHYDROXYXANTHONE-->GENTISIN-->Sodium gentisate-->2,5-Diamino-2,5-cyclohexadiene-1,4-dione
Tag:2,5-Dihydroxybenzoic acid(490-79-9) Related Product Information
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