|
| Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Basic information |
Product Name: | Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate | Synonyms: | METHYL (3R)-3-(TERT-BUTYLDIMETHYL SILYLOXY)-5-OXO-6-TRIPHENYL PHOSPHORANYLIDENE HEXANOATE (J6);B-8
;methyl-(3R)-3-[(terbutyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanoate;Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate;rosuvastatin interMediates J-6;(3R)-3-(tert-butyldiMethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Methyl ester;Methyl (3R)-3-(tert-butyldiMethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanate;(R)-Methyl 3-((tert-butyldiMethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate | CAS: | 147118-35-2 | MF: | C31H39O4PSi | MW: | 534.7 | EINECS: | 604-562-3 | Product Categories: | | Mol File: | 147118-35-2.mol | |
| Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Chemical Properties |
Boiling point | 603.9±65.0 °C(Predicted) | density | 1.10±0.1 g/cm3(Predicted) | storage temp. | Inert atmosphere,Store in freezer, under -20°C | solubility | Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) | form | Solid | color | Pale Yellow to Light Yellow | Stability: | Hygroscopic |
| Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Usage And Synthesis |
Uses | Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities. |
| Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Preparation Products And Raw materials |
Raw materials | Pentanedioic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, 1-anhydride with ethyl carbonate, 5-methyl ester, (3S)--->4-Penten-2-ol, 1-chloro-, (2R)--->5-Hexenenitrile, 3-hydroxy-, (3R)--->5-Hexenoic acid, 3-hydroxy-, methyl ester, (3R)--->3-(tert-Butyldimethylsilyloxy)glutaric anhydride-->(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester-->Triphenylphosphine oxide-->Ethyl chloroformate-->Triphenylphosphine-->Methyl chloroformate-->N,N-Dimethylformamide dimethyl acetal-->Methyltriphenylphosphonium bromide |
|