Fmoc-N-amido-PEG5-azide

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Fmoc-N-amido-PEG5-azide Suppliers list
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
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Company Name: Nanjing Bairuikang Biotechnology Co., Ltd.  
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Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
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Company Name: TargetMol  
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Email: xuexiang.shao@tsbiochem.com
Fmoc-N-amido-PEG5-azide Basic information
Product Name:Fmoc-N-amido-PEG5-azide
Synonyms:Fmoc-N-amido-PEG5-azide;5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 9H-fluoren-9-ylmethyl ester
CAS:2924480-17-9
MF:C27H36N4O7
MW:528.6
EINECS:
Product Categories:
Mol File:2924480-17-9.mol
Fmoc-N-amido-PEG5-azide Structure
Fmoc-N-amido-PEG5-azide Chemical Properties
pka11.598±0.46(predicted)
Safety Information
MSDS Information
Fmoc-N-amido-PEG5-azide Usage And Synthesis
UsesFmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-N-amido-PEG5-azide Preparation Products And Raw materials
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