| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ML338
CAS:1630160-25-6
Package:1removed
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| | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- Basic information |
| Product Name: | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- | | Synonyms: | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- | | CAS: | 1630160-25-6 | | MF: | C17H12ClN5OS | | MW: | 369.83 | | EINECS: | | | Product Categories: | | | Mol File: | 1630160-25-6.mol | ![1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- Structure](CAS/20210305/GIF/1630160-25-6.gif) |
| | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- Chemical Properties |
| Boiling point | 583.4±60.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | pka | -1.60±0.70(Predicted) |
| | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- Usage And Synthesis |
| Uses | ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilliand is against the non-replicatingM. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of theM. tuberculosisbacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy[1]. | | References | [1] Partha P. Nag,et al. Elucidation of the Physiology of Non-Replicating, Drug Tolerant Mycobacterium tuberculosis With the Aid of the Small Molecule Probe ML338. Review PMID:24260778 |
| | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-[[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]thio]- Preparation Products And Raw materials |
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