- 7-bromoindolin-2-one
-
- $36.00 / 1kg
-
2024-04-09
- CAS:320734-35-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 7-bromoindolin-2-one
-
- $15.00 / 1KG
-
2021-07-13
- CAS:320734-35-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 7-bromoindolin-2-one
-
- $15.00 / 1KG
-
2021-07-10
- CAS:320734-35-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 7-bromoindolin-2-one Chemical Properties |
| Melting point | 194-200°C | | Boiling point | 358.8±42.0 °C(Predicted) | | density | 1.666±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 13.22±0.20(Predicted) | | color | White to Light yellow to Light orange |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | Hazard Note | Irritant | | HS Code | 2933790090 |
| | 7-bromoindolin-2-one Usage And Synthesis |
| Preparation | STEP A:
Preparation of 7-chloro-3-hydrazono-oxindole.
A solution of 25.0 g of 7-chloro-isatin in 250 ml of
ethanol is refluxed for 24 hours, cooled, and precipitate
recovered by filtering and washed once with ethanol
and twice with pentane to obtain 7-chloro-3-hydrazono
oxindole, m.p. 217-219℃. (decomp.). STEP B:
Preparation of 7-chloro-oxindole.
To a solution of sodium ethoxide prepared by heating
5.5 g of sodium in 200 ml. of ethanol at 70°℃. is added
17 g of 7-chloro-3-hydrazono-oxindole over a period of
3.5 hours, and the resulting solution is heated at 70℃.
for 24 hours. The solvent is evaporated in vacuo, the
residue dissolved in water, acidified with 6 N-hydro
chloric acid and the resulting precipitate recovered by
filtering, washed three times with water, dried by suc
tion and crystallized from methylene chloride/ether to
obtain 7-chlorooxindole, 28-220℃. |
| | 7-bromoindolin-2-one Preparation Products And Raw materials |
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