| Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:1-Methyluric Acid
CAS:708-79-2
Purity:98% Package:100Mg,10Mg
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| | 1-METHYLURIC ACID Basic information |
| Product Name: | 1-METHYLURIC ACID | | Synonyms: | 1-METHYLURIC ACID;1-METHYL-2,6,8-TRIHYDROXYPURINE;7,9-dihydro-1-methyl-1H-purine-2,6,8(3H)-trione;1-methyl-7,9-dihydro-3H-purine-2,6,8-trione;1-Methyluric acid ,98%;1-Methyluric acid,1-Methyl-2,6,8-trihydroxypurine;1MUA;1-U | | CAS: | 708-79-2 | | MF: | C6H6N4O3 | | MW: | 182.14 | | EINECS: | 211-905-7 | | Product Categories: | Bases & Related Reagents;Heterocycles;Metabolites & Impurities;Nucleotides;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Purines | | Mol File: | 708-79-2.mol |  |
| | 1-METHYLURIC ACID Chemical Properties |
| Melting point | >325°C | | Boiling point | 315.51°C (rough estimate) | | density | 1.5283 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | Refrigerator | | solubility | Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated, Sonicated) | | form | Solid | | pka | 5.60±0.50(Predicted) | | color | Pale Yellow to Pale Brown | | Water Solubility | 1.585g/L(temperature not stated) | | BRN | 195190 |
| WGK Germany | 3 | | HS Code | 29242990 |
| | 1-METHYLURIC ACID Usage And Synthesis |
| Chemical Properties | White to Off-White Solid | | Uses | 1-Methyluric acid, a metabolite of Theophylline, has been used:
for the determination of uric acid in stool samples by liquid chromatography and tandem mass spectrometry
in turbidimetric assay of synthetic urine samples
as a substrate for CYP1A2(cytochrome P450 family 1 subfamily A member 2) assay | | Definition | ChEBI: An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by a methyl group at N-1. It is one of the metabolites of caffeine found in human urine. | | Biochem/physiol Actions | 1-Methyluric acid (1-U) is a major metabolite of caffeine and theophylline with antioxidant activity that protects molecules such as low density lipoproteins (LDL) from oxidative modifications. 1-Methyluric acid may be used in studies aimed at differentiating the activities of caffeine and theophylline metabolites. | | Purification Methods | Recrystallise it from H2O. Its solubility at 17.5o is 1g in 353mL of H2O. [Bergmann & Dikstein J Am Chem Soc 77 691 1955.] It has UV: max at 231 and 283nm (pH 3), and 217.5 and 292.5nm (pH >12) [Johnson Biochem J 5 133 1952]. [Beilstein 26 II 299, 26 III/IV 2621.] |
| | 1-METHYLURIC ACID Preparation Products And Raw materials |
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