- 2-Maleimido acetic acid
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- $15.00 / 1KG
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2021-07-13
- CAS:25021-08-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2-Maleimido acetic acid
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- $15.00 / 1KG
-
2021-07-09
- CAS:25021-08-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2-Maleimido acetic acid
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- $9.80 / 1.79999995231628KG
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2020-01-09
- CAS:25021-08-3
- Min. Order: 1g
- Purity: ≥99%
- Supply Ability: 100kg
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| | 2-Maleimido acetic acid Basic information |
| | 2-Maleimido acetic acid Chemical Properties |
| Melting point | 114 °C(Solv: chloroform (67-66-3)) | | Boiling point | 376.7±25.0 °C(Predicted) | | density | 1.578±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | soluble in DMSO, Methanol | | form | powder to crystal | | pka | 3.31±0.10(Predicted) | | color | White to Almost white | | InChI | InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11) | | InChIKey | GBKPNGVKZQBPCZ-UHFFFAOYSA-N | | SMILES | N1(CC(O)=O)C(=O)C=CC1=O |
| | 2-Maleimido acetic acid Usage And Synthesis |
| Chemical Properties | White to Almost white powder to crystal or Pale Yellow Solid. | | Uses | Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds. | | Application | 2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. | | References | [1] Gabano E, et al. Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. Inorganica Chimica Acta, 2019; 488: 195-200. |
| | 2-Maleimido acetic acid Preparation Products And Raw materials |
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