| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ATR-IN-5
CAS:2601571-19-9
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- manufacturers
- ATR-IN-5
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- $1980.00 / 50mg
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2025-04-27
- CAS:2601571-19-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- Basic information |
| | 1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- Chemical Properties |
| Boiling point | 754.6±70.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | pka | 9.71±0.10(Predicted) |
| | 1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- Usage And Synthesis |
| Uses | ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24)[1]. | | References | [1] Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent CN112047938A. |
| | 1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- Preparation Products And Raw materials |
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