- Monascin
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- $1760.00 / 1mg
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2025-08-21
- CAS:21516-68-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | MONASCIN Basic information |
| Product Name: | MONASCIN | | Synonyms: | MONASCIN;(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione;Monascoflavin;Ccris 9138;(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione;(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione;2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-;Monascin >=97.0% (HPLC) | | CAS: | 21516-68-7 | | MF: | C21H26O5 | | MW: | 358.43 | | EINECS: | | | Product Categories: | | | Mol File: | 21516-68-7.mol |  |
| | MONASCIN Chemical Properties |
| Melting point | 145 °C | | Boiling point | 574.6±50.0 °C(Predicted) | | density | 1.18±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Acetonitrile: Soluble
Chloroform: Soluble | | form | Solid | | pka | 10.59±0.60(Predicted) | | color | Light yellow to yellow | | BRN | 51355 | | InChI | InChI=1S/C21H26O5/c1-4-6-7-9-17(22)18-16-11-13-10-14(8-5-2)25-12-15(13)19(23)21(16,3)26-20(18)24/h5,8,10,16,18H,4,6-7,9,11-12H2,1-3H3/b8-5+/t16-,18+,21-/m1/s1 | | InChIKey | XXKNHBAFFJINCK-RVEJDSBJSA-N | | SMILES | C1(/C=C/C)OCC2C(=O)[C@]3(C)OC(=O)[C@H](C(=O)CCCCC)[C@@]3([H])CC=2C=1 |
| | MONASCIN Usage And Synthesis |
| Uses | Monascin is an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. | | Definition | ChEBI: An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an
methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of car
inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours. | | Biochem/physiol Actions | Monascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors. | | References | [1] WEI-HSUAN HSU . Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice[J]. Food and Chemical Toxicology, 2014, 64: Pages 94-103. DOI: 10.1016/j.fct.2013.11.015
[2] TOSHIHIRO AKIHISA. Anti-Tumor-Initiating Effects of Monascin, an Azaphilonoid Pigment from the Extract of Monascus pilosus Fermented Rice (Red-Mold Rice)[J]. Chemistry & Biodiversity, 2005, 2 10: 1305-1309. DOI: 10.1002/cbdv.200590101
[3] YEU-CHING SHI Tzu M P Vivian Hsiu Chuan Liao. Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans[J]. Free Radical Biology and Medicine, 2012, 52 1: Pages 109-117. DOI: 10.1016/j.freeradbiomed.2011.09.034 |
| | MONASCIN Preparation Products And Raw materials |
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