Adenylyl Imidodiphosphate

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Products Intro: Product Name:Adenosine 5'-(beta,gamma-imido)triphosphate lithium salt hydrate
CAS:25612-73-1
Purity:93% (HPLC), powder Package:5mg;25mg;1mg
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Products Intro: Product Name:Adenosine 5′-(β,γ-imido)triphosphate
CAS:25612-73-1
Purity:>=93% (HPLC) Package:5mg, 10mg, 25mg, 100mg Remarks:A2647
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Products Intro: Product Name:Adenylyl Imidodiphosphate
CAS:25612-73-1
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Products Intro: Product Name:≥93% (HPLC), powder
CAS:25612-73-1
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Products Intro: Product Name:Adenylyl Imidodiphosphate
CAS:25612-73-1
Purity:95% Package:1g;5g;10g
Adenylyl Imidodiphosphate Basic information
Product Name:Adenylyl Imidodiphosphate
Synonyms:Adenylyl Imidodiphosphate;Adenosine 5'-[β,γ-imide]triphosphoric acid;AMP-P(NH)P;AMP-PNP;β,γ-ImidoATP;β,γ-Imido-ATP;5'-Adenylic acid, monoanhydride with imidodiphosphoric acid (8ci,9ci);Adenosine 5'-(beta,gamma-imidotriphosphate)
CAS:25612-73-1
MF:C10H17N6O12P3
MW:506.2
EINECS:277-127-5
Product Categories:
Mol File:25612-73-1.mol
Adenylyl Imidodiphosphate Structure
Adenylyl Imidodiphosphate Chemical Properties
Boiling point 965.5±75.0 °C(Predicted)
density 2.65±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: soluble50mg/mL
form powder
pka1.16±0.50(Predicted)
color white
biological sourcenatural (organic)
Water Solubility H2O: 50mg/mL
BRN 6047109
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
Adenylyl Imidodiphosphate Usage And Synthesis
UsesAdenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has been used in a study to research the effects of monovalent cations Li+, Na+, K+, NH4+, Rb+ and Cs+ on the solid and solution structures of the nucleic acid components. Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has also been used in a study to determine that antidepressants inhibit interferon-γ-induced microglial production of IL-6 and nitric oxide.
UsesAMP-PNP is a competitive inhibitor of most ATP-dependent systems. A good substrate for enzymes hydrolyzing between the α- and β-phosphorus atom, yet is resistant to enzymes cleaving between the β- and γ-phosphorus atom. Substrate of snake venom phosphodiesterase and adenylate cyclase.
AMP-PNP has been used for two-motor fluorescence assay.
DefinitionChEBI: AMP-PNP is an adenosine 5'-phosphate.
General DescriptionAMP-PNP(adenylyl-imidodiphosphate) is an artificial substrate of enzyme, adenylate cyclase. Adenylate cyclase helps to hydrolyze adenylyl-imidodiphosphate slowly than ATP.
Biochem/physiol ActionsA non-hydrolyzable ATP analog. AMP-PNP competitively inhibits ATP-dependent enzyme systems, such as glutamine synthetase. It inhibits a number of enzymes which require the hydrolysis of ATP such as DNA topoisomerase II, SV40 large T-antigen helicase and a number of kinases. Blocks ATP-sensitive calcium-dependent potassium channels.
Adenylyl Imidodiphosphate Preparation Products And Raw materials
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