Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3)

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Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Suppliers list
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Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Basic information
Product Name:Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3)
Synonyms:Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3);Sp-Adenosine-5'-O-(1-thiodiphosphate) (sodium salt);Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium
CAS:2005478-90-8
MF:C10H15N5O9P2S.3Na
MW:0
EINECS:
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Mol File:Mol File
Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Structure
Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Chemical Properties
solubility Water: Soluble
Safety Information
MSDS Information
Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Usage And Synthesis
DescriptionSp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S) is an isomer of the sulfur-containing nucleotide derivative ADP-α-S.1 It is an inhibitor of phosphorylase kinase (Ki = 0.53 µM). Sp-ADP-α-S induces aggregation of isolated human platelets (EC50 = 20 µM).2 It induces relaxation of carbamoylcholine-precontracted guinea pig taenia coli (EC50 = 58.9 µM).3WARNING This product is not for human or veterinary use.
References[1] A CHENG  G M C. Competition between nucleoside diphosphates and triphosphates at the catalytic and allosteric sites of phosphorylase kinase.[J]. The Journal of Biological Chemistry, 1988, 263 12: 5543-5549.
[2] N.J. CUSACK  S. M O H. EFFECTS OF RP AND SP DIASTEREOISOMERS OF ADENOSINE 5′-O-(1-THIODIPHOSPHATE) ON HUMAN PLATELETS[J]. British Journal of Pharmacology, 1981, 73 2: 409-412. DOI: 10.1111/j.1476-5381.1981.tb10437.x
[3] G. BURNSTOCK  L. A M  N J Cusack. Effects of phosphorothioate analogues of ATP, ADP and AMP on guinea-pig taenia coli and urinary bladder[J]. British Journal of Pharmacology, 1984, 82 2: 369-374. DOI: 10.1111/j.1476-5381.1984.tb10771.x
Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3) Preparation Products And Raw materials
Tag:Adenosine, 5′→P′-ester with [P′(S)]-thiodiphosphoric acid ((HO)2P(O)OP(O)(OH)(SH)), sodium salt (1:3)(2005478-90-8) Related Product Information
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