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Testosterone phenylpropionate

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CAS:1255-49-8
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Testosterone phenylpropionate manufacturers

Testosterone phenylpropionate Basic information
Product Name:Testosterone phenylpropionate
Synonyms:TESTOSTERONE 17-PHENYLPROPIONATE--DEA*SC HEDULE III;Stosterone;Androst-4-en-3-one, 17-(1-oxo-3-phenylpropoxy)-, (17.beta.)-;4-androsten-17β-ol-3-one 17-phenylpropionate;Testosterone 17B-phenylpropionate;4-Androstene-17-Oxopropoxyl-3-one-17-phenylpropionate;Testosterone Phenylpropionate (CIII);[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate
CAS:1255-49-8
MF:C28H36O3
MW:420.58
EINECS:215-014-4
Product Categories:API;Steroid and Hormone;Steroids;testosterone;1255-49-8
Mol File:1255-49-8.mol
Testosterone phenylpropionate Structure
Testosterone phenylpropionate Chemical Properties
Melting point 116.5 °C
Boiling point 497.74°C (rough estimate)
density 1.0043 (rough estimate)
refractive index 1.5460 (estimate)
solubility DMF: 25 mg/mL; DMSO: 5 mg/mL; Ethanol: 15 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
Water Solubility 2.25mg/L(25 ºC)
InChIKeyHHSXYDOROIURIP-FEZCWRLCSA-N
SMILES[C@@]12(CC[C@]3(C)[C@H](CC[C@@]3([H])[C@@]1(CCC1=CC(=O)CC[C@]21C)[H])OC(=O)CCC1C=CC=CC=1)[H] |&1:0,3,5,8,10,19,r|
CAS DataBase Reference1255-49-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-40
Safety Statements 22-36
WGK Germany 3
RTECS XA3105000
MSDS Information
ProviderLanguage
SigmaAldrich English
Testosterone phenylpropionate Usage And Synthesis
DescriptionTestosterone phenylpropionate (BAN; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester – specifically, the C17β phenylpropionate ester of testosterone – which was formerly marketed in Romania. It was first synthesized in 1951 and was first described in the literature by 1953. The medication was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren, as well as of Estandron Prolongatum, Lynandron Prolongatum, and Mixogen. TPP was previously available in Great Britain.
UsesTestosterone 17-Phenylpropionate, is one of the 17b-fatty acid esters of testosterone, that is increasingly misused by athletes in an attempt to improve sports performance, and thus can be used in doping control. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.
DefinitionChEBI: Testosterone phenylpropionate is a steroid ester.
Biological FunctionsTestosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester. It was first reported in the scientific literature in 1955 and was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren.
SynthesisSynthesis_1255-49-8In a 100 ml reaction flask, 0.397 g (3 mmol) of cinnamaldehyde was added.0.411g (1.5mmol) Nandrolone, 0.06g (0.3mmol) [Bmim][OAc] catalyst, 10ml 1,4-dioxane, heated to 120 ?? C and then reacted for 2h, after the reaction was completed, cooled to room temperature, added 30 ml of water and 20 ml of ethyl acetate were extracted, and the phases were allowed to stand. The organic phase was concentrated and crystallized to obtain the target product. The yield was 64%.
Testosterone phenylpropionate Preparation Products And Raw materials
Raw materialsCinnamaldehyde-->3-Phenylpropionic acid methyl ester-->Testosterone
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