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| | Dimethylamine hydrochloride Basic information |
| | Dimethylamine hydrochloride Chemical Properties |
| Melting point | 170-173 °C(lit.) | | Boiling point | 95.79°C (rough estimate) | | density | 0.8949 (rough estimate) | | vapor pressure | <0.1 hPa (25 °C) | | refractive index | 1.4202 (estimate) | | storage temp. | Store below +30°C. | | solubility | H2O: soluble0.5g/10 mL | | form | Crystalline Powder or Crystals | | color | White to off-white | | PH | 5 (100g/l, H2O, 20℃) | | Water Solubility | 3000 g/L (20 ºC) | | Sensitive | Hygroscopic | | Merck | 14,3228 | | BRN | 3589311 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | IQDGSYLLQPDQDV-UHFFFAOYSA-N | | LogP | -3.28 | | CAS DataBase Reference | 506-59-2(CAS DataBase Reference) | | EPA Substance Registry System | Methanamine, N-methyl-, hydrochloride (506-59-2) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36/37-37/39-36 | | WGK Germany | 1 | | RTECS | IQ0220000 | | F | 3-9 | | TSCA | Yes | | HS Code | 29211190 | | Toxicity | LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen) |
| | Dimethylamine hydrochloride Usage And Synthesis |
| Description | Dimethylamine hydrochloride is the raw material of organic synthesis, the catalyzer of analysis as an acetylize, and the preparation of azoviolet and dimethylamine aqueous solution. Dimethylamine hydrochloride deoxidation is very capable, and corrodibility is vital, so be usually used in cleaning-type soldering flux. Preparation technology is for slowly splashing into hydrochloric acid in dimethylamine for tradition, and the speed that splashes into is no more than 15 ℃ with temperature, and pH=7-8 is limited. After the reaction finishes, activated carbon decolorizing is added, the filtrate is adjusted to pH=3-4 with hydrochloric acid, decompression is steamed water to the greatest extent, obtaining dimethylamine hydrochloride.
| | Chemical Properties | White, foliage-like crystals with a melting point of 171°C. Highly soluble in water, soluble in alcohol and chloroform, and insoluble in ether. Exhibits deliquescence. | | Uses | Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde. | | Uses | Dimethylamine hydrochloride is a precursor to several industrially significant compounds. | | Uses | As accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg. | | Preparation | Dimethylamine hydrochloride is obtained from the salt formation of dimethylamine and hydrochloric acid. | | Application | Dimethylamine hydrochloride serves as a foundational material for organic synthesis and is utilized as a catalyst and magnesium reagent in acetylation analysis. It has been used in producing hexamethylmelamine-methyl-14C and in preparing standard solutions of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) to assess the presence of methylamines and trimethylamine-N-oxide in particulate matter. | | Flammability and Explosibility | Non flammable | | Purification Methods | Crystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.] |
| | Dimethylamine hydrochloride Preparation Products And Raw materials |
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