ChemicalBook > Product Catalog >API >Synthetic Anti-infective Drugs >Antiviral drugs >Raltegravir


Raltegravir Suppliers list
Company Name: Jinan Chenghui-Shuangda Chemical Co.,Ltd
Tel: +86-13064007766
Products Intro: Product Name:Raltegravir
Purity:99% Package:1KG;5KG Remarks:Enterprise Standard
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Raltegravir
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:518048-05-0
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Raltegravir
Company Name: Biochempartner
Tel: 0086-13720134139
Products Intro: Product Name:Raltegravir
Purity:98% HPLC LCMS Package:10G;20G

Lastest Price from Raltegravir manufacturers

  • Raltegravir
  • US $1.00 / KG
  • 2018-08-21
  • CAS:518048-05-0
  • Min. Order: 1G
  • Purity: 98%
  • Supply Ability: 100KG
Raltegravir Basic information
Product Features
Product Name:Raltegravir
Synonyms:Raltegravir;N-((4-Fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)amino)ethyl)-6-oxo-4-pyrimidinecarboxamide;N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)p;Raltegravir(R&D);Raltegravir(free base);N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide;N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-(2-methyl-1,3,4-oxadiazole-5-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide;N-((4-Fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)am
Product Categories:API;Isentress;Inhibitors
Mol File:518048-05-0.mol
Raltegravir Structure
Raltegravir Chemical Properties
CAS DataBase Reference518048-05-0(CAS DataBase Reference)
Safety Information
MSDS Information
Raltegravir Usage And Synthesis
Product FeaturesMerck's Raltegravir is the first HIV integrase strand transfer inhibitor (referred to as an integrase inhibitor). It is also known as MK-0518, which can treat human immunodeficiency virus (HIV)-1 infection combining with other antiretroviral (ARV) drugs. It slows HIV-1 infection by inhibiting the necessary HIV integrase for viral replication. When raltegravir combines with other anti-HIV drugs, it can reduce the amount of HIV in the blood, while it can increase the number of so-called CD4+ T cells that belong to white blood cells. It helps against other infections. The interaction between raltegravir and ritonavir, efavirenz, tipranavir and tenofovir indicates that there is no drug cross-resistance, and there is a synergistic effect with a variety of drugs. The most common adverse reactions are diarrhea, nausea, headache. In addition, blood tests show that the muscle enzymes abnormally increased in some of patients who taked this drug.
The above information is edited by the chemicalbook of Kui Ming.
UsesRaltegravir (MK-0518, Isentress) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively.
Raltegravir Preparation Products And Raw materials
Tag:Raltegravir(518048-05-0) Related Product Information
Raltegravir Potassium Salt,Raltegravir potassium 2-(1-AMINO-1-METHYLETHYL)-N-(4-FLUOROBENZYL)-5-HYDROXY-1-METHYL-6-OXO-1,6-DIHYDROPYRIMIDINE-4-CARBOXAMIDE Raltegravir Benzyltrimethylammonium chloride Benzyltriethylammonium chloride Phenylacetone CHLOROPHOSPHONAZO III Thiophanate-methyl Sodium lauroylsarcosinate Methyl bromide Parathion-methyl Methyl acrylate Kresoxim-methyl Methyl Benzyl chloride Bensulfuron methyl METHYL THIOPHENE-2-CARBOXYLATE Methylparaben