- Sulbenicillin sodium
-
- $120.00 / 1KG
-
2021-11-27
- CAS:28002-18-8
- Min. Order: 100g
- Purity: 99.99%
- Supply Ability: 5ton/Month
- Sulbenicillin sodium
-
- $15.00 / 1KG
-
2021-07-13
- CAS:28002-18-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Sulbenicillin sodium
-
- $15.00 / 1KG
-
2021-07-10
- CAS:28002-18-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Sulbenicillin sodium Basic information |
| Product Name: | Sulbenicillin sodium | | Synonyms: | sulbenicillindisodium;sulfobenzylpenicillin;sulfocillin;alpha-sulfobenzylpenicillindisodium;sulpelin;SULBENICILLIN DISODIUM SALT;SULBENICILLIN SODIUM;disodium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(r)-2-phenyl-2-sulfonatoacetamido]-4-thia-azabicyclo[3.2.0]heptane-2-carboxylate | | CAS: | 28002-18-8 | | MF: | C16H16N2Na2O7S2 | | MW: | 458.42 | | EINECS: | 248-769-3 | | Product Categories: | antibiotic;API;28002-18-8 | | Mol File: | 28002-18-8.mol |  |
| | Sulbenicillin sodium Chemical Properties |
| | Sulbenicillin sodium Usage And Synthesis |
| Originator | Lillacillin,Takeda,Japan,1973 | | Definition | ChEBI: Sulbenicillin disodium is an organic sodium salt. It contains a sulbenicillin(2-). | | Manufacturing Process | To a suspension of 1.08 parts by weight of 6-aminopenicillanic acid in 8 parts
by volume of water is added 1.48 parts by weight of sodium bicarbonate.
After the mixture is dissolved, a solution of 1.18 parts by weight of α-sulfophenylacetyl chloride in 10 parts by volume of diethylether is gradually
added thereto. The mixture is stirred at a temperature in the neighborhood of
0°C for 1 hour. The aqueous layer is washed twice with 10 parts by volume of
portions of ether and adjusted to pH 1.2 with cation exchange resin of
polystyrene sulfonic acid type under constant cooling. Then the solution is
washed twice with 15 parts by volume of portions of ethyl acetate, followed
by extraction twice with 15 parts by volume of portions of n-butanol. The
extracts are combined and washed twice with 15 parts by volume of portions
of water and, then, extracted with an aqueous solution of sodium bicarbonate.
The extract is adjusted to pH 6.5, washed with ether and lyophilized to give
the sodium salt of α-sulfobenzylpenicillin. Yield is 1.2 parts by weight. | | Therapeutic Function | Antibacterial |
| | Sulbenicillin sodium Preparation Products And Raw materials |
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