七叶胆苷XVII
中文名称 | 七叶胆苷XVII |
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中文同义词 | 七叶胆苷XVII(标准品);七叶胆苷ⅩⅦ;七叶胆苷XVI;七叶胆苷XVII;绞股蓝皂苷XVII;七叶胆苷XVII对照品,;七叶胆皂苷XVII;七叶胆苷XVII(绞股蓝皂苷XVII) |
英文名称 | GYPENOSIDE-XVII |
英文同义词 | GYPENOSIDE-XVII;3β-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside;Gypenoside ⅩⅦ;(3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;Gynosaponin S;GP-17;Gypenoside XVII (Gynosaponin S);β-D-Glucopyranoside, (3β,12β)-3-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl- |
CAS号 | 80321-69-3 |
分子式 | C48H82O18 |
分子量 | 947.15 |
EINECS号 | |
植物来源 | 绞股蓝 |
相关类别 | 标准品;对照品、标准品,植物单体,植物提取物;中药对照品;对照品;植提标准品;植物提取物;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;标准品-中药标准品;三萜;标准品 -中药标准品;标准品,对照品 |
Mol文件 | 80321-69-3.mol |
结构式 |
七叶胆苷XVII 性质
熔点 | >183°C (dec.) |
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沸点 | 1013.5±65.0 °C(Predicted) |
密度 | 1.38 |
储存条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
溶解度 | DMSO(微量)、甲醇(微量)、吡啶(微量) |
形态 | 固体 |
酸度系数(pKa) | 12.90±0.70(Predicted) |
颜色 | 白色至类白色 |
稳定性 | 吸湿性 |
Human Endogenous Metabolite
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The ability of Gypenoside XVII (GP-17) to prevent Ox-LDL-induced cytotoxicity is detected by cell viability assays. Gypenoside XVII does not demonstrate any cytotoxicity in HUVECs. Gypenoside XVII can protect HUVECs against Ox-LDL-induced apoptosis. Gypenoside XVII dose-dependently mitigates the toxic effect of Ox-LDL on HUVEC viability. The viability of HUVECs is significantly higher than that of other groups at 50 μg/mL Gypenoside XVII .
Body weights are measured as physical measures of hormone bioactivity. Mean body weights are significantly higher in every group compared to that of the control, but there is no significant difference in body weight between the different treatments during the 10-week feeding. The mouse plasma lipid levels are also measured at the end of 10 weeks of a high-fat diet. Circulating levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) are significantly increased in the treated groups of ApoE -/- mice compared with those of the C57BL/6J control group; Gypenoside XVII (GP-17) and Probucol treatment substantially decreases both of these parameters relative to those of the ApoE -/- model group.
药理药效:绞股蓝总皂甙具有人参皂甙的适应原作用,其药理作用大致可分为如下方面:1、消炎,抗肠、胃溃疡和肿疡。2、防癌抗癌。3、活化人体正常细胞(起增强体力、活力、耐力、恢复疲劳和延长寿命的作用)。4、镇静和宁神。5、调节类脂代谢。
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/01/25 | HY-N0553 | Gypenoside XVII | 1 mg | 400元 | |
2024/01/25 | HY-N0553 | 七叶胆苷XVII Gypenoside XVII | 80321-69-3 | 5mg | 1000元 |