(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
| 中文名称 | (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) |
|---|---|
| 中文同义词 | 甲状腺激素相关肽[D-TRP12,TYR34]-PTH (7-34) AMIDE (BOVINE);(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) TRIFLUOROACETATE SALT;甲状旁腺激素 [DTRP12, TYR34]-PTH(7-34), -PARATHYROID HOR;化合物 (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE);牛[D-色氨酸12,酪氨酸34]甲状旁腺激素(7-34)酰胺 |
| 英文名称 | (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) |
| 英文同义词 | H-PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2;(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE);THYROID, BOVINE;PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2;(D-Trp12,Tyr34)-pTH (7-34) amide;D-Trp12,Tyr34]-bPTH-(7-34)NH2;(D-Trp??,Tyr??)-pTH (7-34) amide (bovine) trifluoroacetate salt;DTrp12, Tyr34]-pTH(7-34), -Parathyroid Hor |
| CAS号 | 118102-98-0 |
| 分子式 | |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | 标准品 |
| Mol文件 | Mol File |
| 结构式 |
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) 性质
| 储存条件 | -15°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 序列 | Phe-Met-His-Asn-Leu-{d-Trp}-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2 |
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 是一种有效的竞争性甲状旁腺激素 (PTH) 拮抗剂，在牛肾皮质膜中的 Ki 值为 69 nM。(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 可用于生长发育调节。
Ki: 69 nM (PTH)
(D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells.
(D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of Nap
i
T promoted by 1 nM of either PTHrP or PTH.
(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/05/22 | HY-P2426 | (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) | 118102-98-0 | 1mg | 720元 |
| 2025/05/22 | HY-P2426 | (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) | 118102-98-0 | 5mg | 1800元 |