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| 2-Methylindole-3-carboxaldehyde Basic information |
| 2-Methylindole-3-carboxaldehyde Chemical Properties |
Hazard Codes | Xi,Xn | Risk Statements | 36/37/38-22 | Safety Statements | 37/39-26 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29339900 |
| 2-Methylindole-3-carboxaldehyde Usage And Synthesis |
Chemical Properties | Brown powder | Uses | Reactant for preparation of:
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Fluorescent sensors (BODIPY)
- Antimicrobial agents against methicillin-resistant Staphylococcus aureus
- G protein-coupled receptor CRTh2 antagonists
- Inhibitors of PI3 kinase-α
- Antitubercular agents
- Anti-inflammatory agents
- Mycobacterium tuberculosis protein tyrosine phosphatase B
- Glucocorticoid receptor ligands
- Agents stimulating neurite outgrowth
| Uses | Reactant for preparation of:• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• ;Fluorescent sensors (BODIPY)2• ;Antimicrobial agents against methicillin-resistant Staphylococcus aureus3• ;G protein-coupled receptor CRTh2 antagonists4• ;Inhibitors of PI3 kinase-α5• ;Antitubercular agents6• ;Anti-inflammatory agents7• ;Mycobacterium tuberculosis protein tyrosine phosphatase B8• ;Glucocorticoid receptor ligands9• ;Agents stimulating neurite outgrowth10 | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 31, p. 2892, 1983 DOI: 10.1248/cpb.31.2892 | General Description | Oxidative activation of 2-methylindole-3-carboxaldehyde via N-heterocyclic carbene organocatalysis generates heterocyclic ortho-quinodimethane as a key intermediate. |
| 2-Methylindole-3-carboxaldehyde Preparation Products And Raw materials |
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