- ISOPIMPINELLIN
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- $40.00 / 1mL
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2026-02-28
- CAS:482-27-9
- Min. Order:
- Purity: 99.47%
- Supply Ability: 10g
- Isopimpinellin
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- $0.00 / 20mg
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2023-02-24
- CAS:482-27-9
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- isopimpinellin
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- $15.00 / 1KG
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2021-07-02
- CAS:482-27-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | ISOPIMPINELLIN Basic information |
| Product Name: | ISOPIMPINELLIN | | Synonyms: | 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one;4,9-Dimethoxy-furo[3,2-g]chromen-7-one;5,8-Dimethoxy-6,7-furanocoumarin;5,8-Dimethoxypsoralen;5,8-Dimethoxypsoralene;7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dimethoxy-;7H-Furo[3,2-g][1]benzopyran-7-one,4,9-dimethoxy-;ISOPIMPINELLIN | | CAS: | 482-27-9 | | MF: | C13H10O5 | | MW: | 246.22 | | EINECS: | | | Product Categories: | Heterocyclic Compounds;Heterocycles;Coumarins | | Mol File: | 482-27-9.mol |  |
| | ISOPIMPINELLIN Chemical Properties |
| Melting point | 150-151°C | | Boiling point | 448.7±45.0 °C(Predicted) | | density | 1.352±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Soluble in acetone and chloroform; | | form | powder to crystal | | color | Light yellow to Yellow to Green | | Water Solubility | practically insoluble in water | | λmax | 268nm(MeOH)(lit.) | | BRN | 262337 | | InChI | InChI=1S/C13H10O5/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11/h3-6H,1-2H3 | | InChIKey | DFMAXQKDIGCMTL-UHFFFAOYSA-N | | SMILES | C1(=O)OC2=C(OC)C3OC=CC=3C(OC)=C2C=C1 | | LogP | 1.407 (est) | | CAS DataBase Reference | 482-27-9(CAS DataBase Reference) |
| Hazard Codes | T+ | | Risk Statements | 20/21/22-28 | | Safety Statements | 22-36/37/39-45-36/37-28 | | RIDADR | UN 2811 6.1 / PGII | | WGK Germany | 3 | | RTECS | LV1049200 | | HS Code | 2932202000 | | Storage Class | 6.1B - Non-combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Dermal
Acute Tox. 2 Inhalation
Acute Tox. 2 Oral | | Hazardous Substances Data | 482-27-9(Hazardous Substances Data) |
| | ISOPIMPINELLIN Usage And Synthesis |
| Description | Psoralens are natural photoactivable compounds in
plants and can cause phototoxic contact dermatitis.
For example, Cachrys libanotis contains 5,8-dimethoxypsoralen. | | Chemical Properties | Pale Yellow Solid | | Uses | Antiviral, anti HIV | | Uses | antineoplastic, antifungal, insect antifeedant | | Definition | ChEBI: Isopimpinellin is a member of psoralens. | | Hazard | A poison by ingestion. | | Contact allergens | Psoralens are natural photoactivable compounds in plants and can cause phototoxic contact dermatitis. For example, Cachrys libanotis L., Apiaceae-Umbelliferae family, contains 5,8-dimethoxypsoralen. | | Synthesis | General procedure for the synthesis of 4,9-dimethoxyfuro[3,2-g]benzopyran-7-one (Isopimpinellin, 29) from the compound (CAS:14348-23-3) and iodomethane: To a solution of 200 mg (0.9 mmol) of compound 25 in anhydrous DMF (30 mL) was added K2CO3 (286 mg. 2.07 mmol) and CH3I (167 μL, 3.6 mmol). The reaction mixture was heated to reflux under argon protection; after 1 h of reaction, the mixture was poured into cold water (100 mL) and acidified with 1 M aqueous HCl. The product was extracted with ethyl acetate (3 x 50 mL), the organic layers were combined, and the solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by column chromatography (eluent: ethyl acetate/hexane, 1:1). The fraction containing the target compound was collected, concentrated and dried to give 29 as a pale yellow powder (182 mg, 82% yield). | | References | [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 784 - 788 |
| | ISOPIMPINELLIN Preparation Products And Raw materials |
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