| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Nodularin
CAS:118399-22-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Nodularin
CAS:118399-22-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
MedBioPharmaceutical Technology Inc
|
| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:NODULARIN
CAS:118399-22-7
Purity:98% Package:500ug; 100ug; 1mg; 50ug Remarks:Medbio
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Email: |
3003867561@qq.com |
| Products Intro: |
Product Name:Nodularin
CAS:118399-22-7
Purity:HPLC≥98% Package:5mg；10mg；20mg；50mg；100mg；200mg
|
|
| | NODULARIN Basic information |
| Product Name: | NODULARIN | | Synonyms: | tyl-l-arginyl-(2s,3s,4e,6e,8s,9s)-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimeth;yl-10-phenyl-3-aminodecanoyl-d-gamma-glutamyl);NODULARIN;1,4,8,11,15-PENTAAZACYCLONONADECANE, CYCLIC PEPTIDE DERIVATIVE;Nodularin, Nodularia spumigena;1,4,8,11,15-Pentaazacyclononadecane, cyclic peptide;Cyclo((Z)-2,3-didehydro-N-methyl-2-aminobutanoyl-erythro-3-methyl-D-beta-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyl-3-aminodecanoyl-D-gamma-glutamyl);Cyclo(L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-gamma-glutamyl-(2Z)-2-(methylamino)-2-butenoyl-(3S)-3-methyl-D-beta-aspartyl) | | CAS: | 118399-22-7 | | MF: | C41H60N8O10 | | MW: | 824.96 | | EINECS: | 621-437-9 | | Product Categories: | Natural Products | | Mol File: | 118399-22-7.mol |  |
| | NODULARIN Chemical Properties |
| density | 1.29±0.1 g/cm3(Predicted) | | Fp | 11℃ | | storage temp. | −20°C | | solubility | methanol: 2 mg/mL Further dilute to 10% (v/v) methanol. Store solutions at −20°C for up to six months. | | form | Dry residue containing traces of monobasic potassium phosphate. | | pka | 3.39±0.70(Predicted) | | IARC | 3 (Vol. 94) 2010 | | EPA Substance Registry System | Nodularin (118399-22-7) |
| | NODULARIN Usage And Synthesis |
| Description | The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory effect is observed with PP2C, alkaline phosphatase, acid phosphatase, insulin receptor tyrosine kinase, protein kinase A, phosphorylase kinase, or protein kinase C. | | Uses | Nodularin-R is a cyclic peptide toxin produced by freshwater cyanobacteria. | | Definition | Toxin produced by blue green algae. |
| | NODULARIN Preparation Products And Raw materials |
|