(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione

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(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione Basic information
Product Name:(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione
Synonyms:(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione;Onetine【neutral】;2,9-Dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione, 4,7-dihydroxy-4-[(1R)-1-hydroxyethyl]-6,7,14-trimethyl-, (1R,4S,6R,7R)-;Onetine
CAS:41451-67-6
MF:C19H29NO8
MW:399.44
EINECS:
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Mol File:41451-67-6.mol
(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione Structure
(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione Chemical Properties
Melting point 192-3°C
Safety Information
MSDS Information
(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione Usage And Synthesis
DescriptionA hepatotoxic alkaloid from Senecio othonnae M. B., this base is obtained as colourless crystals from MeOH. The alkaloid is dextrorotatory having [α] 20 D + 73° (c 2.5, CHC13). The 12-acetate is identical with Floridanine (q.v.) and the 12: l8-diacetate is Floricaline (q.v.). The flavianate forms colourless crystals from EtOH, m.p. 238-2400 C. The structure has been established from the hydrolysis products, e.g. hydrootonecine and an acid, ClOH1S0 7 , m.p. 142-3°C.
UsesOnetine is a Alkaloids product that can be isolated from the herbs of Senecio othonnae[1].
ReferencesDanilova, Koretskaya, Utkin., J. Gen. Chern., USSR, 32, 647 (1962)
(20R)-15,20-Dihydro-12,15α,20-trihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione Preparation Products And Raw materials
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