|
|
| | 1-Aminonaphthalene-6-sulfonic acid Basic information |
| | 1-Aminonaphthalene-6-sulfonic acid Chemical Properties |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39-24/25 | | RIDADR | 1759 | | WGK Germany | 1 | | RTECS | QK1285000 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29309090 |
| | 1-Aminonaphthalene-6-sulfonic acid Usage And Synthesis |
| Chemical Properties | Purple Solid. 1-Aminonaphthalene-6-sulfonic acid [119- 79-9]. (5-aminonaphthalene-2-sulfonic acid), 1,6-Cleve’s acid, C10H9NO3S, Mr 223.24, crystallizes from boiling water as plates of the dihydrate. Its sodium, potassium, and calcium salts are all readily soluble in water, but the barium salt is only sparingly soluble. Sulfonation with 10 % oleum yields 1-aminonaphthalene-4,6-disulfonic acid. Caustic fusion gives 5- amino-2-hydroxynaphthalene, and Bucherertype hydrolysis gives 1-hydroxynaphthalene-6- sulfonic acid. | | Uses | Intermediate of dyestuff | | Uses | 5-Amino-2-naphthalenesulfonic acid (1,6-Cleve′s acid) was used in the synthesis of nitrate reductase and detection of nitrate reduction by anaerobic bacteria. | | Uses | Fluorescent reagent. | | Definition | ChEBI: 5-aminonaphthalene-2-sulfonic acid is an aminonaphthalenesulfonic acid. | | Production Methods | Sulfonation of 1-naphthylamine with concentrated sulfuric acid at 130℃ gives mainly 1-aminonaphthalene-6-sulfonic acid. However, the latter is always made, together with the 1,7-isomer, by nitration of naphthalene-2-sulfonic acid to give the mixed 5- and 8- nitronaphthalene-2-sulfonic acids follwed by reduction to ‘‘mixed Cleve’s acids.’’ A b-sulfonation mass is diluted with sulfuric acid, then 67.5 % nitric acid is added slowly at 34℃. After being quenched and neutralized with calcium carbonate, the filtered liquor is reduced by boiling with iron powder, slight acidity being maintained with sulfuric acid. After basification with magnesia the iron residues are filtered off and the filtrate is evaporated until the magnesium salt of the product crystallizes on cooling. Filtration followed by washing with magnesium sulfate gives a 34 % yield of the magnesium salt of 1,6-Cleve’s acid. Purification by dissolution in hot water, acidification, and filtration of the free acid while hot reduce the yield to 25 % based on naphthalene. | | General Description | The crystal structure of 5-amino-2-naphthalenesulfonic acid (1,6-Cleve′s acid) depicted the presence of a sulfonate-aminium group zwitterion. |
| | 1-Aminonaphthalene-6-sulfonic acid Preparation Products And Raw materials |
|