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Lufenuron

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Products Intro: Product Name:Lufenuron
CAS:103055-07-8
Purity:98%TC Package:25KG;1000KG
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Products Intro: Product Name:Lufenuron
CAS:103055-07-8
Purity:99% Package:25KG
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Products Intro: Product Name:Lufenuron
CAS:103055-07-8
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Products Intro: Product Name:Lufenuron
CAS:103055-07-8
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Products Intro: Product Name:Lufenuron
CAS:103055-07-8
Purity:99% Package:1kg;100USD

Lufenuron manufacturers

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  • 2024-03-28
  • CAS:103055-07-8
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  • Lufenuron
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  • 2024-02-27
  • CAS:103055-07-8
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Related articles

Lufenuron Basic information
Product Name:Lufenuron
Synonyms:(rs)-1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxyl)phenyl]3-(2,6-difluorobenzoyl)urea;cga-184,699;LUFENURON;Benzamide, N-2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylaminocarbonyl-2,6-difluoro-;lufenuron (bsi,iso,inn);(RS)-1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea;N-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl]-2,6-difluorobenzamide;LUFENURON PESTANAL, 100 MG
CAS:103055-07-8
MF:C17H8Cl2F8N2O3
MW:511.15
EINECS:410-690-9
Product Categories:PROGRAM;103055-07-8
Mol File:103055-07-8.mol
Lufenuron Structure
Lufenuron Chemical Properties
Melting point 174.1°
density 1.631±0.06 g/cm3(Predicted)
vapor pressure <0.4 x10 -3 Pa (25 °C)
Fp 170 °C
storage temp. 0-6°C
solubility 100mg/L in organic solvents at 20 ℃
Water Solubility <0.06 mg l-1(25 °C)
pka8.49±0.46(Predicted)
JECFA Number85
BRN 8398291
InChIKeyPWPJGUXAGUPAHP-UHFFFAOYSA-N
LogP5.12 at 25℃
CAS DataBase Reference103055-07-8(CAS DataBase Reference)
EPA Substance Registry SystemBenzamide, N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro- (103055-07-8)
Safety Information
Hazard Codes Xi;N,N,Xi
Risk Statements 43-50/53
Safety Statements 2-24-37-60-61
RIDADR 3077
WGK Germany 2
HazardClass 9
PackingGroup III
HS Code 29242990
ToxicityLD50 in rats (mg/kg): >2000 orally; LC50 in rats (mg/m3): >2350 (Buholzer)
MSDS Information
Lufenuron Usage And Synthesis
DescriptionLufenuron is an insect development inhibitor of the benzoylphenyl urea class. It demonstrates activity against fleas that have fed on treated cats and dogs and become exposed to lufenuron in the host’s blood. Lufenuron also has activity by virtue of its presence in adult flea feces, leading to its ingestion by flea larvae. Both activities result in the production of eggs that are unable to hatch, causing significant reductions in flea larvae populations. The lipophilicity of lufenuron leads to its deposition in adipose tissues of animals from where it is slowly released into the bloodstream. This permits effective blood concentrations to be maintained throughout the recommended oral dosing interval of 1 month.
UsesLufenuron is used for the control of Lepidoptera and Coleoptera larvae on cotton, maize and vegetables, and of citrus whitefly and rust mites on citrus fruit. It is also used to control fleas on pets and cockroaches in houses.
DefinitionChEBI: Lufenuron is a benzoylurea insecticide, a dichlorobenzene, a N-acylurea, an aromatic ether and an organofluorine compound.
Flammability and ExplosibilityNot classified
PharmacologyAntiparasitic. Lufenuron is a benzoylurea insecticide. This class of insecticides was previously used on fruits to decrease damage by insects. Lufenuron (Program) has been used for prevention of flea infections in dogs and cats because it inhibits chitin synthesis. For this use, it has been given to dogs at a dose of 10 mg/kg every 30 days and to cats at a dose of 30 mg/kg every 30 days. It may also have some inhibition on fungal cell membranes because it inhibits the cell wall of fungi, which contain chitin, and other complex polysaccharides. Because of this property on fungal cell membranes, there has been interest in using lufenuron to treat dermatophytes in small animals. However, proven efficacy has been controversial. Well-controlled studies have not confirmed consistent efficacy for treating dermatophytes in animals.
Veterinary Drugs and TreatmentsLufenuron is approved for use in dogs and cats 6 weeks of age and older for the control of flea populations. The combination product of lufenuron and milbemycin (Sentinel?) is indicated for use in puppies and dogs 4 weeks and older for prevention and control flea populations, prevention of heartworm disease, control of adult hookworms, and the removal and control of adult roundworms and whipworms.
Lufeneron showed initial promise as a treatment for fungal infections, but the early enthusiasm has dampened considerably as efficacy appears doubtful.
Metabolic pathwayOnly limited information is available in the open literature on the metabolism of lufenuron.
DegradationLufenuron is less stable at alkaline pH than under acidic conditions. The DT50 at 25 °C is 160 days at pH 5,70 days at pH 7 and 32 days at pH 9 (PM).
Mode of actionLufenuron has no systemic or translaminar effect. It is persistent with a transovarial effect. It may reduce the egg-Iaying rate or hinder the hatching process of embryos.
Lufenuron Preparation Products And Raw materials
Tag:Lufenuron(103055-07-8) Related Product Information
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