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| | 2'-Hydroxy-5'-methoxyacetophenone Basic information |
| | 2'-Hydroxy-5'-methoxyacetophenone Chemical Properties |
| Melting point | 52 °C(lit.) | | Boiling point | 254.38°C (rough estimate) | | density | 1.1708 (rough estimate) | | refractive index | 1.5500 (estimate) | | Fp | >230 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 10.65±0.18(Predicted) | | form | Crystalline Powder | | color | Yellow | | BRN | 1239364 | | InChIKey | MLIBGOFSXXWRIY-UHFFFAOYSA-N | | CAS DataBase Reference | 705-15-7(CAS DataBase Reference) | | NIST Chemistry Reference | Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-(705-15-7) |
| | 2'-Hydroxy-5'-methoxyacetophenone Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | 2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. 2-Hydroxy-5-methoxyacetophenone is also used to prepare substituted chromanone and chromone derivatives as sirtuin 2-selective inhibitors. | | Preparation | reparation by reaction of dimethyl sulfate on 2,5-dihydroxyacetophenone, ? with potassium carbonate in acetone at r.t. (74%) ; ? with aqueous sodium hydroxide solution at reflux (35%). | | Synthesis Reference(s) | Synthesis, p. 901, 1985 DOI: 10.1055/s-1985-31380 | | General Description | 2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. |
| | 2'-Hydroxy-5'-methoxyacetophenone Preparation Products And Raw materials |
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