| Company Name: |
Chemsky (shanghai) International Co.,Ltd
|
| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:trans-Abacavir-d4 Hydrochloride;(1R,4R)-rel-4-[2-AMino-6-[cyclopropyl-d4)aMino]-9H-purin-9-yl]-2-cyclopentene-1-Methanol Hydrochloride;
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:trans-Abacavir-d4 Hydrochloride
CAS:1346605-40-0
Purity:NULL Package:10mg;1mg Remarks:NULL
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| Company Name: |
Pharma Affiliates
|
| Tel: |
172-5066494 |
| Email: |
@pharmaffiliates.com |
| Products Intro: |
Product Name:trans-Abacavir-d4 Hydrochloride
CAS:1346605-40-0
|
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| | trans-Abacavir-d4 Hydrochloride Basic information |
| | trans-Abacavir-d4 Hydrochloride Chemical Properties |
| | trans-Abacavir-d4 Hydrochloride Usage And Synthesis |
| Uses | trans-Abacavir-d4 Hydrochloride is deuterium labeled trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. | | Uses | The labelled trans-isomer of Abacavir (A104990), a nucleoside reverse transcriptase inhibitor (NRTI). Abacavir USP impurity. |
| | trans-Abacavir-d4 Hydrochloride Preparation Products And Raw materials |
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