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| 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Basic information |
Product Name: | 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile | Synonyms: | 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile;3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile;3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole;1H-Pyrazole-4-carbonitrile, 3-aMino-5-(4-phenoxyphenyl)-;3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile;Ibrutinib intermediates N-3;Zanubrutinib Related Compound 6;Zanubrutinib Impurity 8 | CAS: | 330792-70-6 | MF: | C16H12N4O | MW: | 276.29 | EINECS: | 805-642-2 | Product Categories: | 330792-70-6 | Mol File: | 330792-70-6.mol | |
| 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties |
Boiling point | 585.3±50.0 °C(Predicted) | density | 1.37±0.1 g/cm3(Predicted) | refractive index | 1.699 | Fp | 307.8℃ | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | DMSO (Slightly) | pka | 10.83±0.50(Predicted) | LogP | 3.25298 |
| 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Usage And Synthesis |
Chemical Properties | Light yellow to off-white powder. | Uses | 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck) | Application | 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765). it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor. |
| 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials |
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