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BOC Sciences
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Product Name:Terpendole E
CAS:167427-23-8
Purity:>98% Remarks:Terpendole E is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yame
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| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
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021-51320588 |
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tauto@tautobiotech.com |
| Products Intro: |
Product Name:Terpendole E
CAS:167427-23-8
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CN2-0127-M001
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Terpendole E
CAS:167427-23-8
Purity:>=95% (HPLC) Package:250μg, 1mg Remarks:SML1127
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Terpendole E >=95% (HPLC)
CAS:167427-23-8
Purity:NULL Package:1mg;250ug Remarks:NULL
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| | Terpendole E Basic information |
| Product Name: | Terpendole E | | Synonyms: | Terpendole E;FO 2546L;1-Benzopyrano[5',6':6,7]indeno[1,2-b]isobenzofuro[5,6-e]indole-2-methanol, 3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-4-hydroxy-α,α,4a,12b,12c-pentamethyl-, (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-;Terpendole E >=95% (HPLC) | | CAS: | 167427-23-8 | | MF: | C28H39NO3 | | MW: | 437.61 | | EINECS: | | | Product Categories: | | | Mol File: | 167427-23-8.mol |  |
| | Terpendole E Chemical Properties |
| Boiling point | 597.1±50.0 °C(Predicted) | | density | 1.194±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 14.45±0.70(Predicted) | | form | powder | | color | white to beige |
| | Terpendole E Usage And Synthesis |
| Uses | Acyl-coenzyme A:cholesterol acyltransferase (ACAT) isozymes are involved with cellular cholesterol esterification and regulate intestinal cholesterol absorption and hepatic lipoprotein secretion. Terpendole E is a related compound of Terpendole C (T116600), which is an inhibitor of ACAT1 and ACAT2 isozymes. | | Definition | ChEBI: Terpendole E is an organic heterotricyclic compound and an organooxygen compound. | | Biochem/physiol Actions | Terpendole E is a mitotic kinesin Eg5 (Kinesin-5) inhibitor isolated from Albophoma yamanashiensis that inhibits both motor and microtubule stimulated ATPase activities of human Eg5. Studies indicate that Terpendole E inhibits Eg5 mutants resistant to S-trityl-L-cysteine and other Eg5 inhibitors. Also, Terpendole E is an ACAT (Acyl-CoA:cholesterol acyltransferase) inhibitor. |
| | Terpendole E Preparation Products And Raw materials |
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