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Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate

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Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:KCC009；KCC 009;KCC-009
CAS:744198-19-4
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:KCC009
CAS:744198-19-4
Purity:98% Package:$250.9/5mg;$380.9/10mg;$750.9/25mg;$1200.9/50mg;Bulk package Remarks:98%
Company Name: Shanghai Hekang Biotechnology Co., Ltd.  
Tel: 18939837085
Email: youchemicals@gmail.com
Products Intro: Product Name:Benzyl (S)-1-((3-Bromo-4,5-Dihydroisoxazol-5-Yl)Methylamino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-Ylcarbamate
CAS:744198-19-4
Purity:95+% Package:1g, 5g, 10g, 25g, 100g, 1kg, 1000kg Remarks:C0265
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Products Intro: Product Name:KCC009
CAS:744198-19-4
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Products Intro: Product Name:KCC009
CAS:744198-19-4
Purity:98% HPLC Package:100mg，250mg，1g
Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Basic information
Product Name:Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate
Synonyms:Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate;MRULUIQNANUWTK-ZVAWYAOSSA-N;Carbamic acid, N-[(1S)-2-[[(3-bromo-4,5-dihydro-5-isoxazolyl)methyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxoethyl]-, phenylmethyl ester;KCC 009;KCC009;KCC-009
CAS:744198-19-4
MF:C21H22BrN3O5
MW:476.32
EINECS:
Product Categories:
Mol File:744198-19-4.mol
Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Structure
Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Chemical Properties
storage temp. 4°C, protect from light
solubility DMSO : 250 mg/mL (524.86 mM; Need ultrasonic)
Safety Information
MSDS Information
Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Usage And Synthesis
Biological ActivityKCC009, a transglutaminase 2 (TG2) inhibitor, induces p53-independent radiosensitization[1][2]. The inhibition rates were 15.33±1.46 (%) for H1299/WT-p53 cells, and 14.31±1.90 (%) for H1299/M175H-p53 cells when cells were treated with KCC009 at concentration of 3.91 uM[1].
References[1]. Sheng Huaying, et al. Transglutaminase 2 Inhibitor KCC009 Induces p53-Independent Radiosensitization in Lung Adenocarcinoma Cells. Med Sci Monit. 2016 Dec 21;22:5041-5048. [2]. L Yuan, et al. Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy. Oncogene
Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate Preparation Products And Raw materials
Tag:Benzyl (S)-1-((3-BroMo-4,5-Dihydroisoxazol-5-Yl)MethylaMino)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-YlcarbaMate(744198-19-4) Related Product Information