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PF 06465469 Discontinued See A191400

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PF 06465469 Discontinued See A191400 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:PF-06465469
CAS:1407966-77-1
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:PF-06465469
CAS:1407966-77-1
Purity:98% Package:5mg Remarks:V4445
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:PF-06465469
CAS:1407966-77-1
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:PF 06465469
CAS:1407966-77-1
Purity:98% Package:$216.9/5mg;$335.9/10mg;$756.9/25mg;$1360.9/50mg;$2449.9/100mg;Bulk package Remarks:98%
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-aMino-1H-pyrazolo[3,4-d]pyriMidin-3-yl]-N-(4-isopropyl-5-Methylphenyl)benzaMide
CAS:1407966-77-1
Package:50Mg,5Mg
PF 06465469 Discontinued See A191400 Basic information
Product Name:PF 06465469 Discontinued See A191400
Synonyms:PF 06465469 Discontinued See A191400;(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-aMino-1H-pyrazolo[3,4-d]pyriMidin-3-yl]-N-(4-isopropyl-5-Methylphenyl)benzaMide;PF 06465469;3-[4-Amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-benzamide;(R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide;Benzamide, 3-[4-amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-;PF06465469,PF 06465469;3-[4-amino-1-[(3R)-1-prop-2-enoyl-3-piperidyl]pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-3-methyl-phenyl)benzamide
CAS:1407966-77-1
MF:C30H33N7O2
MW:523.63
EINECS:
Product Categories:Aromatics, Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1407966-77-1.mol
PF 06465469 Discontinued See A191400 Structure
PF 06465469 Discontinued See A191400 Chemical Properties
Melting point 209-212°C
Boiling point 730.2±60.0 °C(Predicted)
density 1.30±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL, clear
pka12.83±0.70(Predicted)
form powder
color white to beige
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
MSDS Information
PF 06465469 Discontinued See A191400 Usage And Synthesis
Chemical PropertiesBeige Solid
UsesPF 06465469 is a covalent Inhibitors of Interleukin-2 Inducible T Cell Kinase (Itk) with nanomolar potency in a whole-blood assay.
Uses(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide is a potential covalent inhibitor of Interleukin-2 Inducible T Cell KInase (Itk). Itk is a member of the TEC-kinase family and is associated with the induction of T cell proliferation and drives cytokines through NFATc.
storageStore at +4°C
PF 06465469 Discontinued See A191400 Preparation Products And Raw materials
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