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| | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Basic information |
| Product Name: | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester | | Synonyms: | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester;(Z)-Methyl 3-(Methoxy(phenyl)Methylene)-2-oxoindoline-6-carboxylate;3-(Methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester;(E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester;Methyl 3-[Methoxy(Phenyl)Methylene]-2-Oxoindoline-6-Carboxylate (Under Development) | | CAS: | 1160293-22-0 | | MF: | C18H15NO4 | | MW: | 309.32 | | EINECS: | | | Product Categories: | Intermediate of BIBF-1120 and PKI587 | | Mol File: | 1160293-22-0.mol |  |
| | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Chemical Properties |
| Melting point | >220oC (dec.) | | Boiling point | 523.8±50.0 °C(Predicted) | | density | 1.273±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 10.62±0.20(Predicted) | | form | Solid | | color | Light Yellow |
| | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Usage And Synthesis |
| Uses | (E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity. |
| | 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester Preparation Products And Raw materials |
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