SB 747651A dihydrochloride manufacturers
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| | SB 747651A dihydrochloride Basic information |
| Product Name: | SB 747651A dihydrochloride | | Synonyms: | SB 747651A dihydrochloride;2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-1H-imidazo[4,5-c]pyridine-7-methanamine dihydrochloride;SB747651A Dihydrochloride,SB 747651A Dihydrochloride;4-[1-Ethyl-7-[(4-piperidylamino)methyl]-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine Dihydrochloride;1H-Imidazo[4,5-c]pyridine-7-methanamine, 2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-, hydrochloride (1:2);SB-747651A Dihydrochloride, 10 mM in DMSO | | CAS: | 1781882-72-1 | | MF: | C16H23ClN8O | | MW: | 378.87 | | EINECS: | | | Product Categories: | | | Mol File: | 1781882-72-1.mol |  |
| | SB 747651A dihydrochloride Chemical Properties |
| solubility | Soluble to 50 mM in water and to 50 mM in DMSO | | form | Solid | | color | White to off-white |
| | SB 747651A dihydrochloride Usage And Synthesis |
| Uses | SB 747651A Dihydrochloride is a useful intermediate. | | in vivo | SB747651A (3 mg/kg; intrascrotal injection) dihydrochloride results in increased neutrophil adhesion 3.5~4.5 hours following stimulation with CXCL2 as compared to the effect of CXCL2[3].
SB-747651A (3 mg/kg; i.p.) dihydrochloride affects neutrophil extravasation by increasing neutrophil emigration only at 3 and 4 hours in mouse peritonitis model of acute inflammation[3]. | Animal Model: | Male C57BL/6N mice (8~16 weeks)[3] | | Dosage: | 3 mg/kg | | Administration: | Intrascrotal injection | | Result: | Resulted in increased neutrophil adhesion 3.5~4.5 hours following stimulation with CXCL2 as compared to the effect of CXCL2. |
| | storage | Desiccate at RT |
| | SB 747651A dihydrochloride Preparation Products And Raw materials |
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