Related articles - Synthesis of Ozanimod Hydrochloride
- Ozanimod Hydrochloride is prepared from the eastern fragment joined to the western fragment to form a central oxadiazole ring ....
- Dec 28，2023
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| | Ozanimod hydrochloride Basic information |
| Product Name: | Ozanimod hydrochloride | | Synonyms: | Ozanimod hydrochloride;Ozanimod hydrochloride Impurity 1;(S)-4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-N-(2-hydroxyethyl)-2,3-dihydro-1H-inden-1-aminium chloride;Ozanimod hyd;(S)-5-(3-(1-((2-Hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile hydrochloride | | CAS: | 1618636-37-5 | | MF: | C23H25ClN4O3 | | MW: | 440.93 | | EINECS: | | | Product Categories: | | | Mol File: | 1618636-37-5.mol |  |
| | Ozanimod hydrochloride Chemical Properties |
| form | Solid | | color | White to off-white | | InChIKey | HAOOCAKHSFYDBU-OZYVVJTJNA-N | | SMILES | N([C@H]1CCC2=C(C3=NOC(C4C=CC(OC(C)C)=C(C#N)C=4)=N3)C=CC=C12)CCO.Cl |&1:1,r| |
| | Ozanimod hydrochloride Usage And Synthesis |
| Description | Ozanimod hydrochloride (RPC-1063 hydrochloride) is an orally available, selective and potent sphingosine 1-phosphate (S1P) receptor modulator that shows high affinity for S1P1 and S1P5. Ozanimod has potential anticancer activity and can be used in studying multiple sclerosis (MS), ulcerative multiple sclerosis (UMS), and other diseases. (MS), ulcerative colitis, coronavirus infections and myelodysplasia. | | Chemical Properties |
Ozanimod hydrochloride is a white to off-white solid with a melting point of ~240°C. It is poorly hygroscopic. The solubility of ozanimod hydrochloride in ethanol and methanol is 1.43 and 2.41 mg/mL; in a pH 5.1, aqueous medium is 3.51 mg/mL. The pKa for this compound is 7.90, and the partition coefficient (logP) is 3.28.
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| | Ozanimod hydrochloride Preparation Products And Raw materials |
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