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| | 1-Hydroxy-2-naphthoic acid Basic information |
| | 1-Hydroxy-2-naphthoic acid Chemical Properties |
| Melting point | 195-200 °C (dec.) (lit.) | | Boiling point | 283.17°C (rough estimate) | | density | 1.2100 (rough estimate) | | refractive index | 1.6310 (estimate) | | Fp | 150 °C | | storage temp. | Sealed in dry,Room Temperature | | solubility | alcohol: freely soluble | | form | Powder or Crystals | | pka | 3.02±0.30(Predicted) | | color | White to slightly pink to tan | | Water Solubility | SOLUBLE IN HOT WATER | | Merck | 14,4834 | | BRN | 974438 | | InChIKey | SJJCQDRGABAVBB-UHFFFAOYSA-N | | LogP | 3.196 (est) | | CAS DataBase Reference | 86-48-6(CAS DataBase Reference) | | EPA Substance Registry System | 1-Hydroxy-2-naphthoic acid (86-48-6) |
| | 1-Hydroxy-2-naphthoic acid Usage And Synthesis |
| Chemical Properties | beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6],
C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in
alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the
4,7-positions. It is sulfonated by oleum to give
the 4-sulfonic and then the 4,7-disulfonic acids.
Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol. | | Uses | Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes. | | Uses | It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff. | | Definition | ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate. | | Preparation | Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product. | | General Description | 1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones. | | Purification Methods | Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.] |
| | 1-Hydroxy-2-naphthoic acid Preparation Products And Raw materials |
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