Azadibenzocyclooctyne-Biotin conjugate manufacturers
- DBCO-Biotin
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- $45.00 / 1mg
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2025-12-03
- CAS:1418217-95-4
- Min. Order:
- Purity:
- Supply Ability: 10g
- DBCO-Biotin
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- $0.00 / 25mg
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2025-06-07
- CAS:1418217-95-4
- Min. Order: 25mg
- Purity: >99.00%
- Supply Ability: 100
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| | Azadibenzocyclooctyne-Biotin conjugate Basic information |
| Product Name: | Azadibenzocyclooctyne-Biotin conjugate | | Synonyms: | Azadibenzocyclooctyne-Biotin conjugate;DBCO-(CH2)2-NH2-BIOTIN;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;DBCO-Biotin | | CAS: | 1418217-95-4 | | MF: | C28H30N4O3S | | MW: | 502.63 | | EINECS: | | | Product Categories: | | | Mol File: | 1418217-95-4.mol |  |
| | Azadibenzocyclooctyne-Biotin conjugate Chemical Properties |
| Boiling point | 905.9±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | -20°C, protect from light, stored under nitrogen | | form | Solid | | pka | 13.90±0.40(Predicted) | | color | White to off-white |
| | Azadibenzocyclooctyne-Biotin conjugate Usage And Synthesis |
| Uses | DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials |
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