| Company Name: |
Shanghai Aladdin Biochemical Technology Co.,Ltd.
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| Tel: |
+86-18521732826 |
| Email: |
market@aladdin-e.com |
| Products Intro: |
Product Name:Rat IgG
Purity:> 95%; Isotype Control Antibody; Rat IgG; Unconjugated Package:10mg/RMB 1999.90;1mg/RMB 359.90;2mg/RMB 539.90
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| | RAT IGG Basic information |
| Product Name: | RAT IGG | | Synonyms: | IGG, RAT;IMMUNOGLOBULIN G, RAT, H AND L;IgG from rat serum;RAT IGG;RAT IGG, WHOLE MOLECULE;RAT IGG, NORMAL;NORMAL RAT IGG | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![RAT IGG Structure]() |
| | RAT IGG Chemical Properties |
| storage temp. | 2-8°C | | form | essentially salt-free, lyophilized powder |
| | RAT IGG Usage And Synthesis |
| Uses | IgG from rat serum has been used:
- To block programmed death ligand 1.
- As a control antibody to study the role of integrin b1 in spindle morphology
- In FACS (flow cytometry) staining
- ELISA (enzyme linked immunosorbent assay)
| | Uses | IgG from rat serum has been used:
- in immunolabeling
- in flow cytometry
- in enzyme linked immunosorbent assay
- as a control in neutrophil depletion assay
Purified rat IgG may be used as a reference antigen, standard, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot immunobinding, Western immunoblotting, immunodiffusion, and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solid phase immunoadsorbents. Rat IgG was used as isotype control in flow cytometry and injected into mice to induce tolerance against rat IgG. | | General Description | IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids, Immunoglobins have two heavy (H) and two light (L) chains, linked by disulphide linkages. Each light chain comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4. IgG antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. Rat IgG is purified from pooled normal rat serum by fractionation and ion-exchange chromatography. | | Biochem/physiol Actions | IgG antibody have enormous therapeutic potential and its fragment crystallizable (Fc) region contributes for the development of therapeutic antibody. |
| | RAT IGG Preparation Products And Raw materials |
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