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| | Mesulfen Basic information |
| Product Name: | Mesulfen | | Synonyms: | DIMETHYL DIPHENYLENE DISULFIDE;MESULPHEN;LABOTEST-BB LT00134652;THIANTHOL;dimethyldiphenylene disulphide;Cutilen;Neosulfine;Peligal | | CAS: | 135-58-0 | | MF: | C14H12S2 | | MW: | 244.38 | | EINECS: | 205-202-4 | | Product Categories: | pharmacetical | | Mol File: | 135-58-0.mol |  |
| | Mesulfen Chemical Properties |
| Melting point | 123° | | Boiling point | bp3 184°; bp14 228-231° | | density | 1.2773 (rough estimate) | | refractive index | 1.6210 (estimate) | | CAS DataBase Reference | 135-58-0(CAS DataBase Reference) |
| | Mesulfen Usage And Synthesis |
| Originator | Mesulfen ,Synopharm GMBH and CO.KG | | Uses | A mixture of dimethylthianthrene and ditoluene-
disulfide. | | Uses | Mesulfen has been used in the study of therapy of seborrhea, seborrheic eczema and acne in a soap base. | | Definition | ChEBI: Mesulfen is a thianthrene. | | Manufacturing Process | 100 parts by weight of toluene, 330 parts of sulfur and 80 parts of aluminum chloride were heated to reflux on the oil bath before the formation of hydrogen sulfide and hydrogen chloride ended. The mixture was poured into water for removing the excess of aluminum chloride. A toluene layer was separated, dried and distilled in vacuum. When toluene was distilled off, about 500 parts by weight the residual yellow oil boiled at 150°-230°C/3 mm Hg was yielded. An objectionable odor was removed by shaking with sodium hydroxide. The residual sulfur (23-25%) was removed by washing with hydrogen peroxide. The residue (mesulfen) looked like fragile asphalt mass after distillation. | | Therapeutic Function | Scabicide |
| | Mesulfen Preparation Products And Raw materials |
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