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| | Ethyl diethoxyphosphinylformate Basic information |
| | Ethyl diethoxyphosphinylformate Chemical Properties |
| | Ethyl diethoxyphosphinylformate Usage And Synthesis |
| Chemical Properties | Clear colorless to slightly yellow liquid | | Uses | Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral. | | General Description | for synthesis | | Purification Methods | Dissolve it in Et2O, shake this with H2O (to remove any trace of NaCl impurity), dry (Na2SO4), evaporate and distil it using an efficient fractionating column. [Nylén Chem Ber 57 1035 1924, Reetz et al. J Am Chem Soc 77 3813 1955, Monson Advanced Organic Synthesis Academic Press p 89 1972, Beilstein 3 II 103.] |
| | Ethyl diethoxyphosphinylformate Preparation Products And Raw materials |
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