- Flupirtine
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- $15.00 / 1KG
-
2021-07-13
- CAS:56995-20-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Flupirtine
-
- $15.00 / 1KG
-
2021-07-10
- CAS:56995-20-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Flupirtine Basic information |
| Product Name: | Flupirtine | | Synonyms: | CARBAMIC ACID;FLUPIRTINE;D-9998;Katadolon;Ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate;FLUPIRITNE MALEATE;[2-Amino-6-[[(4-fluorophenyl)methyllaminol-3-pyridinyl]carbamic acid ethyl ester;Carbamic acid, [2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester | | CAS: | 56995-20-1 | | MF: | C15H17FN4O2 | | MW: | 304.32 | | EINECS: | 260-503-8 | | Product Categories: | | | Mol File: | 56995-20-1.mol |  |
| | Flupirtine Chemical Properties |
| Melting point | 115-116° | | Boiling point | 445.15°C (rough estimate) | | density | 1.350±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Soluble in DMSO | | form | Powder | | pka | 12.19±0.70(Predicted) | | Water Solubility | 1g/L(temperature not stated) |
| Toxicity | LD50 orally in mice, rats: 617, 1660 mg/kg (Jakovlev) |
| | Flupirtine Usage And Synthesis |
| Uses | Analgesic. | | Uses | Therapeutic use of Flupirtine was discontinued due to drug induced liver injury (DILI). Since the mechanism of action is not related to its adverse effects, it is important to focus on chemical modifications. | | Definition | ChEBI: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester is an aminopyridine. | | Clinical Use | Flupirtine maleate is an
analgesic with an unknown mode of action. It is
used in single doses of 100 mg orally and 150
mg rectally for the treatment of different pain
conditions. |
| | Flupirtine Preparation Products And Raw materials |
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