- Piroctone olamine
-
- $0.00 / 25Kg/Drum
-
2024-04-26
- CAS:68890-66-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 200mt/year
- Piroctone olamine
-
- $0.00 / 1KG
-
2024-04-26
- CAS:68890-66-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1000 TONS
|
| Product Name: | Piroctone olamine | | Synonyms: | 2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1);4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon;octopiroxolamine;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1);Hydroxyl pyrazole ketones;1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine;1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl);-one compound with 2-aminoethanol (1:1) | | CAS: | 68890-66-4 | | MF: | C16H30N2O3 | | MW: | 298.43 | | EINECS: | 272-574-2 | | Product Categories: | bacteriostatic and fungistatic;ARAMINE;OLED materials,pharm chemical,electronic;PP;68890-66-4;1 | | Mol File: | 68890-66-4.mol |  |
| | Piroctone olamine Chemical Properties |
| Melting point | 134.0 to 138.0 °C | | Boiling point | 135-235℃[at 101 325 Pa] | | density | 1.1[at 20℃] | | vapor pressure | 0-0Pa at 20-25℃ | | storage temp. | Inert atmosphere,2-8°C | | solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) | | pka | 5.9-7.4[at 20 ℃] | | color | White to Off-White | | Water Solubility | 400-50000mg/L at 20-25℃ | | Merck | 14,7502 | | InChI | InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 | | InChIKey | BTSZTGGZJQFALU-UHFFFAOYSA-N | | SMILES | C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C | | LogP | 1.05-3.86 at 20-25℃ | | CAS DataBase Reference | 68890-66-4(CAS DataBase Reference) |
| WGK Germany | 2 | | RTECS | UU7786150 | | HS Code | 2933399090 |
| | Piroctone olamine Usage And Synthesis |
| Description | Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the treatment of fungal infections.Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone. | | Appearance | White or slightly yellow crystalline powder.
| | Solubility | Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water or in 1%-10% ethanol; slightly soluble in water and in oil. The solubility in water varies by pH value, and is a litter larger in neutral or weak basic solution than in acid solution.
| | Toxicity | Acute toxicity : Acute oral LD50 –rat 8100mg/kg, practically nontoxic.
Subchronic toxicity : NOEL: 100mg//kg/d (rat, orally, 3 months).
Chronic toxicity and carcinogencity : Negative.
Mutagenicity : Negative.
Irritation to skin and eye : Very low.
| | Uses | Piroctone Olamine is an anti-dandruff agent used in shampoo formulations. | | Uses | Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma. | | Definition | ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone. | | Brand name | Octopirox (Hoechst AG, Germany). | | Side effects |
It should be kept in mind that shampoos with Piroctone Olamine should not be used more than twice a week, unlike other daily-use shampoos that don't have this ingredient. One of the biggest side effects of Piroctone Olamine is that it can cause irritation and itchiness on the head.
|
| | Piroctone olamine Preparation Products And Raw materials |
|