H-GLY-TYR-PRO-GLY-GLN-VAL-OH manufacturers
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| H-GLY-TYR-PRO-GLY-GLN-VAL-OH Basic information |
Product Name: | H-GLY-TYR-PRO-GLY-GLN-VAL-OH | Synonyms: | GLY-TYR-PRO-GLY-GLN-VAL;H-GLY-TYR-PRO-GLY-GLN-VAL-OH;PROTEINASE ACTIVATED RECEPTOR 4 AGONIST PEPTIDE (GYPGQV), HUMAN;PAR-4 AGONIST PEPTIDE (GYPGQV), HUMAN;PAR-4 (1-6) (HUMAN);PAR 4 (1-6);GYPGQV, Coagulation Factor II Receptor-Like 3 (1-6) (huMan), Proteinase Activated Receptor 4 (1-6) (huMan), ThroMbin Receptor-Like 3 (1-6) (huMan);Glycyl-L-tyrosyl-L-prolyl-glycyl-L-glutaminyl-L-valine trifluoroacetate salt | CAS: | 225779-44-2 | MF: | C28H41N7O9 | MW: | 619.67 | EINECS: | | Product Categories: | | Mol File: | 225779-44-2.mol | |
| H-GLY-TYR-PRO-GLY-GLN-VAL-OH Chemical Properties |
storage temp. | -15°C | solubility | H2O: >2mg/mL | form | powder | color | white to tan |
| H-GLY-TYR-PRO-GLY-GLN-VAL-OH Usage And Synthesis |
Description | PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4R47A when used at a concentration of 500 μM. PAR4 (1-6) induces platelet aggregation of isolated washed human platelets when used at a concentration of 1 mM but does not affect clotting time induced by factor VIIa, soluble tissue factor, and collagen in an ex vivo coagulation assay. |
| H-GLY-TYR-PRO-GLY-GLN-VAL-OH Preparation Products And Raw materials |
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